You searched for "oropharynx"
Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...
Impact of the updated cancer staging system on HPV-positive disease
The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...
How common is oropharyngeal dysphagia amongst the adult population?
It is well known that oropharyngeal dysphagia (OD) is a symptom arising from many different aetiologies or disease conditions and that it is a significant morbidity affecting people’s quality of life. Establishing the prevalence of OD is complicated by the...Observations and ruminations - a week of collaboration and learning in Ghana
A week of surgical exchange in Ghana reveals the power of collaboration, resilience and mutual learning in advancing global ENT care. Isabelle JM Williams. Isabelle’s perspective It was a Saturday lunchtime at Heathrow airport, terminal 3. Professor David Howard, Miss...The pioneer of precision: Wolfgang Steiner and the evolution of transoral laser surgery
It is rare that a single clinician entirely changes the course of the management of a particular condition. Steiner was one such clinician. Wolfgang Steiner was to transoral laser microsurgery what Grandmaster Flash was to hip-hop or James Brown was...
Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...
Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)
There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...
Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma
Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...
Long-term effectiveness of sleep surgery for obstructive sleep apnoea
n this study, 39 patients from Turkey with obstructive sleep apnoea (of varying severity) underwent an expansion sphincter pharyngoplasty. This operation was devised by Prof Kenny Pang in Singapore and involves using the palatopharyngeus muscle and partly relocating it laterally...Head and neck cancer deaths to cost $535 billion by 2030
More than 500,000 people across the globe will die this year from head and neck cancer, which is the sixth most common cancer in the world and comprises malignancies of the nose, mouth, throat, larynx, and neck. Assuming current trends...
