Journal Reviews

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Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma

30 April 2020 | | Head and Neck | human papillomavirus, oropharyngeal cancer, overall survival, pack-years, smoking status

Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...