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Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis
It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...
Surviving oropharyngeal squamous cell carcinoma – does subsite matter?
Human papilloma virus (HPV) status is a known prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC). The eighth edition of American Joint Cancer Committee (AJCC) has modified the TNM staging to reflect this. However, subsite as an independent prognostic factor...
Do you really like me? Is it, Is it therapy?
Therapeutic alliance describes what happens in the interactions and relationships between the client and the therapist. There is evidence from mental health literature that a therapeutic alliance can have a significant impact on outcomes. A negative alliance can lead to...
Rib grafts for mandibular reconstruction
Reconstruction of the mandible following ablation requires good bone stock to allow optimal function and the placement of dental implants. In the developed world, vascularised bony flaps are accepted as the gold standard but these may not be widely available...
What the people want and need: emerging service for communication needs in Ghana
There is a significant shortfall in rehabilitation service for people with communication difficulties across Majority World countries. It is known that many people in these countries are likely to seek help from a variety of sectors including western healthcare, religious...
Olfactory protective effect of omega-3 supplements during healing after endoscopic sellar and parasellar resection
This multicentre study, led by researchers from Stanford, demonstrates another use for omega-3 supplements. The study analysed cohorts equally divided between control arm and omega-3 supplementation. Post endoscopic sellar and parasellar resection, better olfactory function was observed at three and...
Role of imaging in unilateral sensorineural hearing loss
Recent understanding of the significance of unilateral hearing loss in children for language development calls for extensive investigations and early rehabilitation. This retrospective study of 90 children with unilateral hearing loss with high resolution CT scans and MRI revealed that...
Clinical pathological features associated with malignant change in oral leukoplakias
This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...
To scan or not to scan, otosclerosis
Otosclerosis can co-exist with other ear pathologies such as superior semicircular canal dehiscence (SSCD). Stapedectomy in this situation can lead to development of SSCD symptoms. Authors conducted an email-based survey involving active members of the American Neurotologic Society (ANS) and...
Justice for all: role of registered intermediaries
The United Nations’ Agenda for Sustainable Development 2015 advocates equal access to justice for all. In recognition of this, a number of countries have introduced a new professional role; a registered intermediary in England, Wales and NI. The registered intermediary...
Non-surgical and surgical management of arytenoids granuloma
Arytenoid granulomas are often a sequelae of laryngopharyngeal reflux (LPR). Unless there is suspicion of malignancy, they require a very balanced approach between conservative management and surgical intervention. The authors present a series of 62 patients with whom the primary...
