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Sublingual house dust mite immunotherapy
House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...
What blood tests should be requested to investigate vocal cord paralysis?
Patients who are discovered to have a vocal cord palsy with no obvious cause on history or examination routinely undergo investigations to exclude an underlying pathology. Cross-sectional imaging of the relevant recurrent laryngeal nerve is required, but considerable variability has...
How does the Dizziness Handicap Inventory (DHI) correlate with demographics and symptoms of patients?
The DHI is widely used to assess the self-perceived emotional, functional and physical disability in subjects with dizziness and balance problems. By studying the data of 568 patients retrospectively, the authors sought to determine the gender and age differences in...
Previous radiotherapy does not cause worse outcomes in patients with differentiated thyroid cancer
Radiation exposure from nuclear incidents, especially in childhood, is known to increase the risk of thyroid cancer. This large retrospective study from the Memorial Sloan Kettering Cancer Centre sought to determine if thyroid cancers in patients with prior exposure to...
Surgery or medicine: when should we stop trying to be conservative?
Although most otolaryngologists would agree that surgery improves the outcomes of patients with CRS when medical treatment has failed, both Cochrane reviews state that there is no proof of improved efficacy of surgery over medicine – however, that was after...
PACT or Partners of Aphasic Clients Conversation Training
There is an increasing recognition that families and caregivers of patients require special training to manage their wards. PACT or Partners of aphasic patients Conversation Training is an initiative which aims to improve awareness of methods of communicating with aphasic...
Airway intervention for epiglottitis
This Japanese study was a retrospective review of 83 patients admitted with epiglottitis over a 9.5-year period. The authors found that the factors that were significantly more likely to be present in patients who received airway intervention were: odynophagia; drooling;...
Microbiome changes after endoscopic sinus surgery: all is not what it seems
As we keep fighting a losing battle with bacteria and antibiotics, it becomes clear that it is not about killing bacteria, not even diminishing the bacterial load, but rather about shifting the different types of bacteria that colonise and live...
Sinus surgery effects on asthma patients
Chronic rhinosinusitis (CRS) and asthma are related. The authors identified a gap in the literature and designed this study with a relatively large sample size of 86 patients. They included patients with comorbid asthma and CRS with or without polyps...
FESS for recurrent acute rhinosinusitis: at last, some data
As noted in both the EPOS 2012 and in the (more recent) ICARS 2016, there is a paucity of evidence on the effectiveness of surgery for recurrent acute rhinosinusitis (RARS). The authors used a control group of patients with CRSsNP,...
Risk of malignancy in non-diagnostic thyroid FNACs
Thyroid nodules are present in between 21-68% of the general population. The evaluation of these nodules to exclude thyroid carcinoma includes fine-needle aspiration cytology (FNAC) and a non-diagnostic cytology result occurs between 8-20% of the time. This retrospective cohort study...
