You searched for "chemotherapy"

248 results found

Malignant craniopharyngiomas

Craniopharyngiomas are successfully managed with surgery and / or adjuvant chemoradiotherapy. The transnasal endoscopic route has become increasingly utilised in the management of these challenging tumours. This paper reviews 23 cases from the literature of the rarely reported malignant transformation....

Can comorbidities predict complications after total laryngectomy? Utility of the Modified Frailty Index (mFI) score

Decision making regarding appropriate treatment for laryngeal cancer is complex. Patients undergoing total laryngectomy experience significant changes in anatomy and physiology and are at risk for significant postoperative complications. These patients represent a group with significant comorbidities. In addition, patients...

Pharyngocutaneous fistula after total laryngectomy

Pharyngocutaneous fistula (PCF) after total laryngectomy is a serious complication post-surgery, and can lead to prolonged hospitalisation, adding delays in postoperative chemoradiotherapy. This Turkish retrospective study looked at 166 patients who underwent total laryngectomy for laryngeal cancer, although it is...

Setting up a robotic surgical practice: view from India

Transoral robotic surgery has an established role in head and neck cancer surgery. But how easy is it to set up a service in a resource-constrained environment? Gouri Pantvaidya and Ameya Pai give us a view from the Indian subcontinent....

Retrieval of an aspirated voice prosthesis in the awake laryngectomised patient

In this article, the authors describe a simple and effective technique for extracting an aspirated voice prosthesis from within the tracheobronchial tree in the awake laryngectomised patient using the Ambu® aScopeTM 4 Broncho endoscope. Surgical voice restoration remains the dominant...

Pomegranate juice as an otoprotective agent

Chemotherapeutic agents such as cisplatin, given alongside irradiation, offer a survival advantage in head and neck cancer. Some patients often complain bitterly about side-effects of their treatment, one of which is ototoxicity. In this paper, the authors propose the use...

Sylvester O’Halloran Surgical Scientific Meeting 2023

Clifton Wijaya presenting the best oral/poster to Teja Kaare, University of Limerick Medical Student with Professor Calvin Coffey in the background. Professor John E Fenton, Consultant in Academic ORL-HNS University Hospital Limerick and current President UEMS-ORL. The Head and Neck...

Smoking and immunotherapy – does it worsen outcome?

This interesting study aimed to address the issue of smoking in patients who had their allergic rhinits treated by sublingual immunotherapy (SLIT). Assessment was with validated quality of life questionnaires. There were 163 patients recruited in Greece who had completed...

Sublingual house dust mite immunotherapy

House dust mite immunotherapy in allergic rhinitis was shown to be effective in trials with a relatively small number of participants. The authors of this study performed a multicentre double-blind randomised controlled trial to investigate effects of house dust mite...

Role of ultrasonography-guided fine-needle aspiration in management of the neck after chemoradiotherapy

Primary chemoradiotherapy (CRT) is a well-established treatment for locally advanced head and neck squamous cell carcinoma (HNSCC). However, not every patient has a complete response to this treatment modality, necessitating eventual salvage neck dissection. Some patients with persistent adenopathy following...

Prophylactic swallowing exercises in head and neck cancer

Clinicians working in head and neck cancer will be familiar with the increased interest in prophylactic swallowing exercises to reduce the devastating impact of dysphagia experienced by patients undergoing radiation or chemo-radiation therapy. This study from Denmark is one of...

Age and vocal cord carcinoma

As the population ages, the management of vocal fold carcinomas should be evaluated. In this retrospective study on 33 patients aged 75 and more, the authors compared the results of radiotherapy and endoscopic treatment for T1 and T2 glottic carcinoma....