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In this issue...Inner Ear Therapeutics

Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Ralph Holme, Director of Research and Insight, RNID, UK. Ralph. E: Holme@rnid.org.uk W: www.rnid.org.uk For Mar/Apr 2022, we sang the...

Cochlear implants and therapeutics: a natural partnership?

Global awareness of cochlear implants as a solution for hearing loss is slowly increasing and gaining acceptance. The potential for combining cochlear implants with inner ear therapeutics is immense, with promise in several areas. This article takes us on a...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

4th Annual Inner Ear Disorders Therapeutics Summit

Terrri Gaskell, Chief Technology Officer, Rinri TherapueticsHeld in Boston, USA, this was an essential gathering that captured the growing excitement in both the biotech and clinical communities surrounding the rapid advancements in hearing loss therapies. With the potential to significantly...

5th Annual Inner Ear Disorders Therapeutics Summit

Coined by industry as the only meeting of its kind and uniquely positioned to share fresh ideas and assess viable approaches to your most pressing preclinical, translational, and clinical bottlenecks, the 5th Inner Ear Disorders Summit returns as a forum to benchmark learnings from past failures, reignite momentum and develop investment into the audiology therapeutic landscape.

Implantation Otology & Inner Ear Therapeutics Issue I

To skip directly to features, click the links below: Welcome from the editor - by Prof Manohar Bance Industry News Genomic therapies for hearing loss - by Manohar Bance Cell-based therapies - by Jennifer Harre, Athanasia Warnecke, Hinrish Staecker, Eva...

Team proves secure pathway to the inner ear

An international team of surgeons and scientists has, for the first time, validated safe surgical access to the central core of the human cochlea.

Rethinking tinnitus ‘care’: the role of digital solutions

Experiencing tinnitus can be very distressing and accessible care is limited. Digital therapeutics is one way of addressing these concerns, as described by Dr Bardy. Tinnitus presents a significant clinical challenge for various healthcare professionals, including general practitioners (GPs), ENTs...

Do you really like me? Is it, Is it therapy?

Therapeutic alliance describes what happens in the interactions and relationships between the client and the therapist. There is evidence from mental health literature that a therapeutic alliance can have a significant impact on outcomes. A negative alliance can lead to...

Therapeutic alliance: more than the ‘nice person’ effect

Therapeutic relationship is considered a key component of many healthcare interventions, including speech and language therapy. Yet definitions and descriptions of what this concept comprises are ambiguous and sparse. This scoping review used the Joanna Briggs Institute guidelines to guide...