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212 results found

Incidental paranasal sinus fungal balls

Fungal ball (FB) sinusitis, also referred to as mycetoma or aspergilloma, is a chronic non-invasive mycotic disease. This study aimed at analysing the natural history and outcomes of patients with incidental paranasal FB on imaging. This was a retrospective study...

Vocal fold motion impairment following intubation – how likely is it to recover?

Ed’s Choice reviews a timely paper investigating prolonged intubation on vocal fold motion. The current scientific literature is dominated by studies examining COVID-19 and its widespread effects on health and healthcare delivery but will be old news by the time...

Salivary Gland Neoplasms

Salivary Gland Neoplasms is another useful addition to the Advances in Otolaryngology series. This issue (Vol 78) sees Prof Patrick Bradley (Nottingham) and David Eisele (Baltimore) co-edit a 206-page edition, nicely divided into 23 chapters, covering basics like molecular pathology,...

An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?

Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....

Adjuvant intratympanic steroid therapy in sudden sensorineural hearing loss

Sudden sensorineural hearing loss (SNHL) means abrupt hearing loss by 30dB affecting three consecutive frequencies within 72 hours. This is treated by high tapering doses of systemic steroids, the role of which is controversial and fraught with possible complications in...

Endoscopic findings and prediction of outcome in unilateral vocal cord paralysis

Unilateral vocal cord paralysis which is not due to irreversible causes such as malignancy, systemic disease or trauma varies considerably in terms of full recovery and restoration of voice. Usually electromyography is used to make possible predictions, but this facility...

Rare, aggressive pituitary adenomas

This is a review article on published cases of the rare Crooke’s pituitary adenoma. These tumors are usually invasive and may be clinically aggressive; they may be endocrinologically silent or may produce adrenocorticotropic hormone causing Cushing’s disease. They often recur...

Red flag head and neck cancer symptoms

This was a prospective study of 1589 patients that were enrolled in the Scottish Audit of Head and Neck Cancer between 1999 and 2001. It recorded their presenting symptoms and assessed their long-term survival with respect to symptoms and subsites...

Ultrasound assessment of metastatic disease

This Japanese study of 10 patients over 15 years, assesses the role of ultrasonography in assessing metastatic disease to the thyroid gland, specifically renal clear cell carcinoma (RCCC). Whilst uncommon, the authors state that there is a favourable prognosis when...

The stigma of HPV in oral cancer

The increase of oropharyngeal carcinoma (OPC) in the developed world seems to be largely caused by infection with the human papillomavirus (HPV). HPV is a group of 150 DNA viruses that are common and most people will be infected at...

The unknown primary again

In this retrospective study of 35 patients, the authors followed a systematic protocol for the detection and management of malignant cervical lymph nodes without an apparent primary lesion. Although their one, three and five year survival results are consistent with...