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The hidden dementia in motor neurone disease
It is now well recognised that people with motor neurone disease (also known as amyotrophic lateral sclerosis) are at risk of developing frontotemporal dementia. It can be difficult to recognise the symptoms of cognitive decline in this group due to...IAOO 2025
Jason Fleming, Reader/Hon Consultant Head & Neck Surgeon, Liverpool Head and Neck CentreThis July, Liverpool became the beating heart of global oral oncology, welcoming almost 1200 delegates for the 10th World Congress of the International Academy of Oral Oncology (IAOO)....
Basic principles of bioengineering and regeneration
The ability to create de novo tissue to replace that removed from patients during surgery is a relatively recent advance. However, this is a fast-moving field and one which surgeons must be aware of from practical, ethical and scientific viewpoints....
Narrow band imaging in the management of carcinoma of unknown primary
This was a retrospective study to assess the utility of narrow band imaging (NBI) in the detection of a primary site in carcinoma of unknown primary (CUP). Patients with CUP who underwent transoral robotic surgery (TORS) and preoperative imaging with...
Another paper advocating resection templates
Resection in the head and neck region leads to complex defects with significant impairment in function. Reconstruction is even more difficult and to improve the accuracy of both resection and reconstruction a number of aids are used. With the improved...
Trends in the incidence of oropharyngeal cancer
The recent rise in HPV-related oropharyngeal squamous cell carcinoma is well described. There has been a significant shift from tobacco-driven to virus-driven cancers at this anatomical site. This retrospective study analysed US tumour registry data over a long period (1973–2009)...
Total lower lip reconstruction: a review
Total or near total defects of the lower lip may result from trauma, cancer ablation or congenital causes. Defects usually involve the full thickness and include skin, muscle and mucosa. There are a number of techniques for the one stage...
Head and neck radiation and the brain
An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Nasal function in COVID-19 patients
This Turkish prospective study compared SNOT-22 outcomes as well as objective assessments of nasal secretion and clearance in 40 patients who tested positive on COVID-19 antigen PCR testing and 40 patients who tested negative. Sinonasal findings were assessed using a...Establishing a medical device company: an ENTrepreneur’s experience
In 2004, while I was suturing the mucopericondrial flaps for a septoplasty, I thought to myself, “there must be an easier and faster way of doing this”. Even though I had no formal training in business or medical device development,...
