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IAOO 2025
Jason Fleming, Reader/Hon Consultant Head & Neck Surgeon, Liverpool Head and Neck CentreThis July, Liverpool became the beating heart of global oral oncology, welcoming almost 1200 delegates for the 10th World Congress of the International Academy of Oral Oncology (IAOO)....Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...4th Annual Inner Ear Disorders Therapeutics Summit
Terrri Gaskell, Chief Technology Officer, Rinri TherapueticsHeld in Boston, USA, this was an essential gathering that captured the growing excitement in both the biotech and clinical communities surrounding the rapid advancements in hearing loss therapies. With the potential to significantly...
The hidden dementia in motor neurone disease
It is now well recognised that people with motor neurone disease (also known as amyotrophic lateral sclerosis) are at risk of developing frontotemporal dementia. It can be difficult to recognise the symptoms of cognitive decline in this group due to...30 Years Experience with Pettigrew Temporal Bones
The Glasgow Temporal Bone Course was started in 1976, by Mr Alastair Pettigrew using cadaver bones. However, because of changes in the law in the UK, these became unavailable in the middle 90s and the course had to use the...
Basic principles of bioengineering and regeneration
The ability to create de novo tissue to replace that removed from patients during surgery is a relatively recent advance. However, this is a fast-moving field and one which surgeons must be aware of from practical, ethical and scientific viewpoints....
Another paper advocating resection templates
Resection in the head and neck region leads to complex defects with significant impairment in function. Reconstruction is even more difficult and to improve the accuracy of both resection and reconstruction a number of aids are used. With the improved...
Trends in the incidence of oropharyngeal cancer
The recent rise in HPV-related oropharyngeal squamous cell carcinoma is well described. There has been a significant shift from tobacco-driven to virus-driven cancers at this anatomical site. This retrospective study analysed US tumour registry data over a long period (1973–2009)...
Total lower lip reconstruction: a review
Total or near total defects of the lower lip may result from trauma, cancer ablation or congenital causes. Defects usually involve the full thickness and include skin, muscle and mucosa. There are a number of techniques for the one stage...
Head and neck radiation and the brain
An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
