You searched for "allergy"
Location, location, location: How to get the steroid where you need it, in chronic rhinosinusitis
What almost all current guidelines on chronic rhinosinusitis have in common is the importance of intranasal steroid (INCS) use. However, it is increasingly understood that the efficacy of INCS depends on their efficient delivery to the point of need, i.e....
Persistent symptoms of smell loss after COVID-19 infection
Anosmia as a result of COVID-19 infection is well recognised. This timely and topical French paper looks at 115 patients with proven SARS-CoV-2 infection, who were contacted with specific questions about olfactory and gustatory disturbance. They found 81% of patients...
Antibiotics in orthognathic surgery
This paper from the Netherlands looked at 137 patients over a one-year period, 18 of whom had Le Fort I procedures, 68 bilateral sagittal split surgery, and 51 bi-maxillary surgery. A further 54 surgical procedures were undertaken, including 15 having...
Can we avoid FESS in patients with true isolated odontogenic sinusitis?
This is a useful study looking at how best to manage patients with odontogenic sinusitis and if FESS can be safely avoided. The authors treated patients by removing the odontogenic cause of the rhinosinusitis by extracting the offending tooth and...
COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?
COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...
CRS vs. migraine: which is the culprit in most headaches?
‘Sinus headache’ is a common diagnosis according to patients and primary care physicians, but relatively infrequent in the eyes of otolaryngologists. This study examines 104 patients with a primary headache syndrome (PHS) and 130 patients with CRS, looking at SNOT-22...
How much does FESS improve the sense of smell?
We are all familiar with patients who undergo a seemingly successful FESS but, in spite of this, have persistent smell dysfunction postoperatively. This study compares a surgical group with a control group, measuring olfactory function pre and postoperatively using Sniffin...
A new era in the treatment of recalcitrant nasal polyps?
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...
How safe is sinonasal surgery for the operating surgeon in times of COVID-19?
I’m sure we have all wondered how safe we are in the operating theatre from virus circulating in the room and therefore the risk of subsequent COVID-19 infection. The authors addressed this by measuring the airborne particle concentrations in the...
Serum biomarkers for CRSwNP
This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...
Why do some people get their smell back so quickly after a COVID infection whilst others don’t?
Of course, we are all too familiar with the effect that COVID-19 infection has on our sense of taste and smell, but why do most patients get better whilst, for many, the misery lingers on and on? This paper looks...
