Journal Reviews

American Journal of Otolaryngology cover image.

A new era in the treatment of recalcitrant nasal polyps?

8 November 2021 | | Laryngology / Swallowing / Voice, Rhinology / Sinus | IgE, SNOT-22, aspirin-exacerbated respiratory disease, chronic rhinosinusitis with nasal polyps, mild asthma, nasal polyps, omalizumab, quality of life, tissue eosinophilia, total nasal endoscopic polyp score

Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...

ALLERGY cover

Chronic rhinitis endotypes

1 November 2019 | | Auditory Implants | chronic rhinitis, cluster analysis, endotype, local IgE, serum IgE

Chronic rhinitis (CR) is common with up to 30% of the population affected, with a significant impact on quality of life. CR includes several phenotypes with different pathogenesis including allergy, autoimmune, age, occupation, pregnancy, neurogenic and drugs. Such variation means...