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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...News from Soluvos Medical
Autumn is about to start and everyone had hoped that social life, travel and meetings would be back to normal.Soluvos Medical wishes you a healthy 2022!
The team at Soluvos Medical hopes that 2022 will bring social life, travels and meetings back to normal and that everyone can meet up at one of the scheduled meetings in the first quarter of 2022.Laryngology: past, present and future
Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...Dispelling myths about audiologic counselling: part one
In the first of a two-part series (see Part 2 here), Drs Clark and English explore common misconceptions in audiologic counselling and highlight the power of empathy and person-centred care. As patients sit before us, they experience any number of...Patient-centred and accelerating progress: two organisations changing the landscape for rare skull base tumours
Patient-led organisations are transforming care for rare skull base tumours by connecting patients, clinicians and researchers to accelerate diagnosis, support and scientific progress. A skull base tumour diagnosis is a difficult time for any patient, but it is made more...Connected hearing healthcare: the realisation of benefit relies on successful clinical implementation
Connected hearing healthcare is the one of best tools for improving access to, as well as the overall quality, of hearing healthcare. Evelyn Davies-Venn and Danielle Glista discuss the benefits and important factors that contribute to successful implementation of this...A place for everything and everything in its place: the practicalities of randomised clinical trials
Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...
A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars
This single blinded RCT compared 43 patients with 50 symptomatic keloids that were randomised to two matched groups of 25 scars, receiving either 5-fluorouracil (5-FU) or current first line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments was unblinded,...
