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Papzimeos: a major advance in treating adult recurrent respiratory papillomatosis

Since the beginning of our specialty, generations of patients and surgeons have faced the challenging clinical problem of recurrent respiratory papillomatosis (RRP). Driven by a persistent and chronic infection with low-risk human papillomavirus (HPV) types 6 or 11, it is...

Nasal sidewall reconstruction

Expert reconstruction of nasal sidewall defects requires careful selection of techniques across nasal layers, balancing aesthetics, structural support and patient needs. When reconstructing a nasal skin defect, a variety of factors should be taken into account in order to achieve...

In conversation with Jeff Small and Navid Shahnaz

The impact of COVID-19 has been felt on all levels of society and deeply affected our lives. It has challenged us to find new ways of carrying on with our activities at home, work, and school. Jeff Small, Director and...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

Current considerations on neural development and hearing loss in young children

The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...

Congenital CMV: investigations and management in the audiology setting

Congenital cytomegalovirus (cCMV) is the only cause of congenital sensorineural hearing loss (SNHL) for which there is a medical treatment available to prevent further hearing loss. Dr Simone Walter discusses cCMV infection, cCMV-related hearing loss, and how to facilitate their...

Rhinoplasty for cleft nose deformity

Modern cleft lip and palate repairs produce excellent functional and aesthetic results at an early age. Tony Holmes, a craniofacial surgeon with over 40 years’ experience, shares his wisdom on the best timing and techniques for addressing the associated complex...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...