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The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

Clinicopathological features of follicular variant of papillary thyroid carcinoma

The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...

Salivary Gland Neoplasms

Salivary Gland Neoplasms is another useful addition to the Advances in Otolaryngology series. This issue (Vol 78) sees Prof Patrick Bradley (Nottingham) and David Eisele (Baltimore) co-edit a 206-page edition, nicely divided into 23 chapters, covering basics like molecular pathology,...

Coblation for lingual haemangiomas

Haemangiomas are benign vascular tumours characterised histologically by a marked proliferation of blood vessels. They can be either congenital or acquired, and can affect the tongue, both within the oral cavity and the oropharynx. A variety of interventions exist for...

Pulse synchronous tinnitus

This article reviews the most common neurosurgical causes of pulse synchronous tinnitus. Traditionally, tinnitus has been characterised as subjective vs. objective, or vascular vs. nonvascular. The authors observe that, in some cases, pulsatile tinnitus (PT) is not heard by examiners...

Structures determining T4a, T4b

This paper for tertiary cancer centre in India attempted to determine whether patients with T4b oral cancers involving the 'masticator space' should be treated with survival intent comparable to T4a cancers. Over a 7-year period, 30 patients with T4b cancers...

Review of pituitary tumour pathology

This is an excellent review article covering the pathology of pituitary adenomas (PA) as well as rare sellar lesions like lymphocytic hypophysitis that require aggressive treatment. The authors have preserved the 2017 World Health Organization (WHO) classification of PA and...

Preventing major postoperative haemorrhage following TORS

Transoral robotic surgery (TORS) has become an increasingly utilised treatment modality in the management of oropharyngeal squamous cell carcinoma (OPSCC). Postoperative haemorrhage, although uncommon, is a significant complication. To ameliorate this risk, transcervical ligation of branches of the external carotid...

Potential benefits of turbinate sparing medial maxillectomy

Whilst endoscopic medial maxillectomy (EMM) has good results as the standard treatment option for tumours arising in the maxillary sinus, postoperative problems of crusting, epiphora and paraesthesia are not uncommon. This paper looks at modified EMM aimed at sparing the...

Clinical histopathology of 250 parotidectomy patients

Clinical histopathology of 250 parotidectomy patients This is a retrospective study of 250 consecutive parotidectomy patients at units in Belgium and the Netherlands. The sensitivity and specificity of FNAC was 64% and 99% respectively, the sensitivity being slightly lower than...

Narrow band imaging improves diagnosis of malignant laryngeal lesions

The manufacturers of narrow band imaging (NBI) claim better visualisation of mucosal abnormalities when compared with simple white light. The primary aim of the study was to compare the diagnostic accuracy of NBI and white light to diagnose malignant laryngeal...

An eye-opening resection technique

It is widely accepted that the gold standard treatment of inverted papilloma of the maxillary sinus (IPMS) is endoscopic excision via medical maxillectomy or mega antrostomy, and these approaches can be augmented by a Caldwell-Luc or canine fossa trephination if...