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Helicobacter pylori infection delays mucociliary clearance in the nose
Chronic rhinosinusitis is not uncommonly a difficult condition to treat and therefore any possible association of this condition with factors outside the nose and sinuses is the subject of worthwhile research. Impairment of mucociliary clearance is paramount to upper respiratory...
Voice and unilateral vocal fold paralysis
Voice outcomes are the main comparators when managing unilateral vocal fold paralysis (UVP). In a review of the literature, 11 voice indicators are included in 80% of all articles. However, when surgeons were surveyed on their clinical preferences and their...
More than words: looking at all the evidence
Evidence based practice (EBP) is a three-pillared approach whereby information on the research evidence, factors relating to the patient and clinical experience are all considered to inform a care decision. Unfortunately, there is frequently very little research evidence to inform...
The septum and breathing
The authors compared the improvement in nasal obstructive symptoms in two groups of patients. One group underwent septoplasty alone and the other septoplasty accompanied with compensatory turbinoplasty. They used the Nasal Obstruction Symptom Evaluation (NOSE) [12] and visual analog scale...
Stepwise approach to manage palatal myoclonus successfully
Palatal myoclonic tinnitus (PMT) is a rare condition caused by rhythmic voluntary or involuntary movements of the soft palate, mainly the tensor veli palatini and levator veli palatine muscles. Patients usually present with a ‘clicky’ noise in the ear. Oral...
Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
CRS vs. migraine: which is the culprit in most headaches?
‘Sinus headache’ is a common diagnosis according to patients and primary care physicians, but relatively infrequent in the eyes of otolaryngologists. This study examines 104 patients with a primary headache syndrome (PHS) and 130 patients with CRS, looking at SNOT-22...
Serum biomarkers for CRSwNP
This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...
Septoplasty under local and general anaesthetic
This Turkish prospective, non-randomised study compared the quality of life outcomes in 50 patients who underwent local anaesthetic (LA) septoplasty, and 50 patients who underwent general anaesthetic (GA) septoplasty over a six-month period. Quality of life outcomes were measured using...
Speech predictors after glossectomy
This is a cross-sectional study from India where 69 patients were assessed for speech intelligibility and phonetics using an assessment tool in the local language. Volume defects were classified into thirds and the location of this defect noted. Not unsurprisingly,...
To scan or not to scan?
This comprehensive review article seeks to establish how useful is MRI in the evaluation of patients with a history of smell loss or distortion. Interestingly, while some studies found the imaging unhelpful, one paper described found a 25% rate of...
