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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

The use of repositioning chairs in the diagnosis and treatment of BPPV

The authors performed a systematic review assessing the utilisation of multi-axial repositioning chairs, such as the TRV chair and the Epley Omniax Rotator, in the diagnosis and treatment of BPPV. They reviewed nine studies, of which four were prospective studies....

Dysphagia in people with HPV-related oropharyngeal cancer

Human papilloma virus (HPV) associated oropharyngeal cancers are becoming much more prevalent and, in some geographic areas, have overtaken tobacco as the leading cause of oropharyngeal cancer. HPV-associated cancers are also reported to have better prognosis in general, and research...

Can tympanometry be used to diagnose Ménière’s disease?

The authors proposed multifrequency tympanometry (MFT) as an in-office test which may be able to diagnose Ménière’s disease (MD) that is quicker and more cost-effective than other methods. MFT measures the acoustic admittance of the middle ear and external ear...

Remote consultations: bringing ENT in to the 21st century

The ongoing peaks and troughs of the COVID-19 pandemic have imposed unprecedented challenges on day-to-day healthcare provision that we all took as given across the globe prior to spring 2020! The pandemic has, in many ways, made us push boundaries...

Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...

Detecting hearing loss in the military: are the current methods adequate?

A team at the University of Southampton have been funded by the Ministry of Defence to investigate how to improve the assessment of auditory fitness for duty in the UK Armed Forces. Matt Blyth talks us through the current methods...

Cocaine-induced ENT pseudo-GPA (CIEpGPA): an underdiagnosed entity

Cocaine-induced ENT pseudo-GPA is increasingly seen in our ENT clinics. The authors of a new ENT UK guideline offer a concise overview for day-to-day recognition and management. Use of cocaine has steadily increased in Europe since 2010 and now represents...

Persistent dysphonia due to cricothyroid muscle dystonia – should we be requesting laryngeal EMGs for non-resolving ‘functional’ dysphonia?

This article is an interesting report of a case of persistent voice problems affecting a 43-year-old physician that significantly compromised her ability to converse and communicate at work. Specifically, she had a fluctuating voice quality that would ‘choke off’, combined...

Clinical value of 3 T magnetic resonance imaging after intratympanic gadolinium injection in cases of delayed endolymphatic hydrops

Recurrent vertigo can continue after severe unilateral or bilateral hearing loss. This is a condition similar to Ménière’s disease, the diagnosis of which can be difficult. In this study intratympanic injection of gadolinium-diethylenetriamine penta-acetic acid dimeglumine was done in 25...

In conversation with Dr Peter Belafsky

Dr Peter Belafsky. Peter – tell us about your background I was born in Philadelphia and went on to study at Vassar College which is a small liberal arts school in upstate New York. I then attended Medical School in...

Doing it for yourself: self-management in speech and language therapy

People with stroke aphasia are traditionally discharged from speech and language therapy when they have plateaued; meaning they are making no further progress in language recovery. This service model has been problematic, leading to people being discharged when they are...