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Chronic rhinosinusitis update

There is still a lack of awareness of chronic rhinosinusitis (CRS) despite its burden, calling for events such as the recent Global Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Awareness Day. Research findings from recent publications by Backaert et al have...

Rhinology and Skull Base Surgery – From the Lab to the Operating Room: an Evidence-based Approach

There have been many attempts to comprehensively address the topic of ‘Rhinology’, however Georgalas and Fokkens in their new book Rhinology and Skull Base Surgery – From the lab to the operating room: an evidence-based approach, have managed to deliver...

Adenoidal hypertrophy in children with allergic rhinitis

Nasal congestion in children with allergic rhinitis can be confounded by adenoidal hypertrophy. This retrospective Turkish study examines this association in more detail. The sample studied was 566 children (age 2-18) that were diagnosed (based on ARIA guidelines) and treated...

Retained surgical cottonoids in the nose

his is an interesting group of case reports essentially documenting the presence and characteristics of retained surgical packing (non-resorbable) post sinus surgery. Paranasal gossypiboma refers to surgical foreign objects such as sponge or patties that are left in the nose;...

Omalizumab for CRSwNP: a monoclonal antibody

A prospective study from London, evaluating the response of chronic rhinosinusitis patients with nasal polyposis who were being treated with monoclonal antibody against IgE for severe allergic asthma. Thirteen patients were treated with Omalizumab, according to UK guidelines for their...

Facial pain and headaches

This paper reviews the present knowledge and the recent publications on the cause, characteristics, course and treatment of chronic and recurring facial pain and headaches. Facial pain should be defined in terms of frequency, duration and severity, and also in...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

Loss of smell in the age of COVID-19

Loss of smell (LOS) is a debilitating symptom with increasing interest for the medical community due to its high prevalence in COVID-19. In the present paper, a team of 15 experts provide recommendations for the investigation and management of patients...

Is wine blocking your nose?

Salicylates are commonly found in a wide variety of foods, such as unripe fruit, vegetables, nuts, seeds and spices. They play a role in growth and development of plants, photosynthesis, transpiration, ion uptake and transport. Non-steroidal exacerbated respiratory disease (N-ERD)...