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Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis

It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...

Bilateral medialisation thyroplasty for presbylaryngis

This retrospective case series explores the voice outcomes for 21 patients diagnosed with presbylaryngis who underwent bilateral medialisation thyroplasty at a university medical centre in Portland, Oregon, USA. Silastic was implanted in 17 patients; hydroxyapatite in four. Significant improvements were...

Inverted papilloma

This Croatian study aimed to look at risk factors associated with malignant transformation and recurrence in 91 cases in a single institution over a 20-year period. There were 66 men and 25 women included in the study. The authors reported...

PET-CT for malignant nasopharyngeal lesions

This retrospective Turkish review of 92 patients aimed to determine the ability of fluorine 18-fluorodeoxyglucose (FDG) maximum standardised uptake value (SUVmax) on positron emission tomography/computerised tomography (PET/CT) to differentiate benign processes and malignant nasopharyngeal lesions. The authors retrospectively reviewed the...

Ultrasound-guided core biopsy of neck lumps as first-line investigative modality supersedes fine needle aspiration cytology in the diagnosis of neck lumps

Ultrasound-guided fine needle aspiration cytology (USFNAC) when applied as initial investigation often proves non-diagnostic, the incidence being as high as 50% in a recent audit. In this study, the authors applied ultrasound-guided core biopsy (USCB) to neck lumps over 1cm...

Occurrence of cancer in asymmetrical tonsillar enlargement in adults

With significant increase in head and neck cancer in the last decade, attributed to HPV, fast-track referrals from primary care have markedly increased, adding further to the burden on the NHS. Whether or not unilateral tonsillar enlargement alone, without red...

Is pan-endoscopy necessary to detect synchronous primary in upper aerodigestive tract cancer?

Diagnosis of head and neck cancer requires speed. It has also to be comprehensive in view of the possibility of synchronous primary cancer (SPC) associated with upper aerodigestive tract cancer (UADTC). Some centres still consider pan-endoscopy essential in the diagnostic...