You searched for "allergy"

820 results found

Recurrent seroma in cochlear implanted patients

Little is known about why some patients experience recurrent seromas over the implant package and in the absence of any cause, antibiotics are frequently prescribed as a precaution to protect the implant from infection. A tertiary referral centre selected five...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

An advance in imaging for sinonasal tumours?

Benign sinonasal growths are incredibly common, and malignant sinonasal growths thankfully rare. We know that malignant tumours often present late, and the imaging can sometimes be misleading, so the authors here compare using diffusion weighted imaging (DWI), dynamic contrast enhanced...

A new treatment for smell loss?

It has been well established that smell training can be effective in the recovery of smell function post Covid-19 infection, and many other treatment modalities have been assessed. There have been limited studies to date evaluating the effects of dietary...

Not the answer yet, but it may be in the future

AI is certainly a topical issue these days and radiomics refers to techniques which allow the extraction of quantitative features from medical imaging to produce large data sets for clinical problem solving. This paper looks at CT imaging of the...

Early recognition aiding better prognosis?

As we are all aware, acute invasive fungal rhinosinusitis (AIFR) is a life-threatening disease which typically affects immunocompromised patients. It is diagnosed via typical signs, symptoms and presentation but gold standard is by biopsy of tissues demonstrating infiltration fungal hyphae....

Fungal rhinosinusitis

Allergic fungal rhinosinusitis (AFRS) has been defined by the following characteristics: presence of nasal discharge, nasal obstruction, decreased sense of smell or facial pressure for 12 weeks, mucin within the sinus cavity containing fungal hyphae and degranulating eosinophils, endoscopic evidence...

What I look for at a conference (and why you should go to BACO 2023)

Professor Claire Hopkins has attended more than her fair share of international meetings, and she shares her top tips. COVID has changed the face of medical education forever – who would have thought only a few years ago that we...

A brief overview on chronic facial pain in rhinology practice

Chronic facial pain is a common yet complex issue in rhinology, often neurologic in origin and frequently misattributed to sinus disease. Facial pain is a very common complaint in the rhinology clinic. In a community-based ENT practice where patient symptoms...

Nasal allergies and OSA

The first day of June is the meteorological start of summer. As a moderately wet spring slowly blurs to (a damp UK) summer, we can look forward to holidays in the countryside, enjoying the changing pollen seasons from tree to...

Are upper respiratory symptoms and macroscopic changes in children always due to gastro-oesphageal reflux?

In children, symptoms such as chronic cough, wheezing, stridor, voice changes, persistent asthma and dental erosion are often presumed to be due to gastro-oesophageal reflux and empirical treatment with PPIs is offered. Usual investigations, such as a barium meal, gastroscopy...