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An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer
Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...Mentally and physically safe workplaces: the challenge of doctors’ well-being
Our ENT consultant colleague Eric Levi bravely tackles the very real elephant in the room of that stigma which is not really discussed until it is often too late. It takes courage to tackle a difficult topic like doctors’ mental...Audiological evaluation and management of teenagers with tinnitus
There is a growing interest in investigating, understanding and managing tinnitus in children and adolescents, with several articles on the subject published in journals over the last year. Brian Fligor describes the approaches to consider when discussing tinnitus with teenagers....Balance and vestibular disorders in children
Discover the world of paediatric vestibular assessment and management from the team at Alder Hey Children’s Hospital, which is revolutionising services in this field. Dizziness and balance problems generate significant morbidity in children of all age groups. Vestibular disorders are...
Effect of COVID-19 on hearing and balance
Rhinological symptoms are cardinal features of COVID-19. However there have only been anecdotal reports on the involvement of the ear, the closest neighbour to the nose and throat. The aim of this study was ‘to assess the presence of persistent...
IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
Applying ‘Sal classification’ to parotid cytology to replicate the success of the Thy classification system
The usefulness of the Thy classification in thyroid gland disease has led to attempts to generate a similar cytology classification for parotid lesions. However, the accuracy of fine-needle aspiration cytology in salivary gland disease is more variable because of the...
