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Nasal nitric oxide – an inflammatory marker in paediatric allergic rhinitis?
Nasal nitric oxide (nNO) is mainly produced in the paranasal sinus mucosa and was shown in some studies to have increased expression in allergic rhinitis (AR). Although it represents a potential non-invasive tool for AR measurement, there remains no consensus...
Using SNOT-22 to predict revision sinus cases
A simple way of predicting which patients will require revision endoscopic surgery does not yet exist. This study, which is a prospective, longitudinal cohort study, part of the UK national audit, aims to predict this by using a relatively simple,...
Retained surgical cottonoids in the nose
his is an interesting group of case reports essentially documenting the presence and characteristics of retained surgical packing (non-resorbable) post sinus surgery. Paranasal gossypiboma refers to surgical foreign objects such as sponge or patties that are left in the nose;...
Is the lack of sunshine the reason behind allergic rhinitis?
Deficiency in Vitamin D, an in vogue immunomodulator, has been shown in emerging data to have a substantial pathogenetic role in allergic related diseases, particularly asthma. The concept of a shared upper and lower airway has allowed the natural extrapolation...
Approaching a ranula
The March issue of Operative Techniques in Otolaryngology is the first of two concentrating on oral surgery within the paediatric setting. It sets the scene with a paper on the anatomy of the paediatric oral cavity and the associated surgical...
Supplementing intranasal cortical steroids with montelukast: does it help?
Intranasal steroids are widely used in the treatment of allergic rhinitis. Whether or not the addition of montelukast helps was assessed in this study. This was a single centre prospective randomised double-blind placebo-controlled trial of two groups of patients, one...
Risk of second primary cancer among patients with head and neck cancers
Patients with head and neck squamous cell carcinoma (HNSCC) have an elevated risk of developing a second primary malignant neoplasm (SPMN). These are of increasing concern because the number of survivors of HNSCC has been growing owing to early detection...
From a dysphagia clinical trial to a multidisciplinary head and neck clinical pathway – the road to implementation
This paper describes the barriers and facilitators to establishing a structured and coordinated multidisciplinary care pathway for patients with head and neck cancer at a medical centre in the USA. The initiative was set in motion by the roll out...
A trial of house dust mite sublingual tablet in children with allergic rhinitis
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...
Doing it for the people: how to do speech and language therapy
This review article distils 58 studies, collating information from people with aphasia, their families and clinical speech and language therapists summarising the seven habits of highly effective aphasia therapists. Habit 1: Effective therapists invest time in and prioritise relationships with...
Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma
Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...
