Journal Reviews

Neurosurgery journal cover image.

Molecular and genetic nature of skull base tumours drives management

3 May 2022 | | Skull Base Surgery | Adamantinomatous craniopharyngioma, Chordoma chondrosarcoma, Endolymphatic sac tumor, Granular cell tumor, Langerhans cell histocytosis, Meningioma, Neuropathology, Papillary craniopharyngioma, Paraganglioma, Pituicytoma, Pituitary adenoma, Pituitary blastoma, Schwannoma, Skull base tumors, Solitary fibrous tumor, Spindle cell oncocytoma

This article reviews the molecular basis and paradigm shift in the diagnosis and management of skull base tumours. It is now known that the phenotype of meningiomas is influenced by their genotype. Endolymphatic sac tumours are observed in up to...

Prostaglandin versus leukotriene receptor-antagonists in treatment of seasonal allergic rhinitis RCT phase II

1 January 2018 | | Bayesian posterior probability, allergic rhinitis, leukotriene receptor antagonist, mast cell degranulation, prostaglandin D2 receptor 1 antagonist

Seasonal allergic rhinitis is very common. Failure to control the disease with mono-therapy leads to dual therapy treatment with less compliance and reduced quality of life. A prostaglandin receptor antagonist (ONO-4053) showed some efficacy in controlling allergic rhinitis in animal...

Approaching a ranula

1 September 2015 | | ranula, mucocele, plunging ranula, sublingual gland, floor of mouth, neck mass, pediatric

The March issue of Operative Techniques in Otolaryngology is the first of two concentrating on oral surgery within the paediatric setting. It sets the scene with a paper on the anatomy of the paediatric oral cavity and the associated surgical...