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4842 results found

Less pain more gain: impact of prophylactic gabapentin on swallowing outcomes in head and neck cancer patients undergoing radiation treatment

Patients planned for chemoradiation to the head and neck are usually advised to expect some pain and soreness during their treatment and that pain relief will be offered as and when it is required. Uncontrolled pain and mucositis affect oral...

Voice change after total thyroidectomy with intact laryngeal nerves – a common but temporary problem

It has been reported that up to 87% of patients have a degree of voice dysfunction after thyroidectomy, even when the laryngeal nerves are preserved. Postoperative inflammation, laryngeal oedema due to vascular congestion, direct damage to the cricothyroid muscles and...

Omalizumab for CRSwNP: a monoclonal antibody

A prospective study from London, evaluating the response of chronic rhinosinusitis patients with nasal polyposis who were being treated with monoclonal antibody against IgE for severe allergic asthma. Thirteen patients were treated with Omalizumab, according to UK guidelines for their...

Using cVEMPs to distinguish between vestibular migraine and from Ménière’s

Vestibular migraine (VM) and Ménière’s disease (MD) could overlap or mimic each other. Since the use of cVEMPs became routine, attempts have been made by researchers to explore its clinical utility in these two conditions. In this prospective study, the...

Hypoglossal stimulation for OSA

Continuous positive airway pressure (CPAP) is a highly effective treatment for moderate-to-severe obstructive sleep apnoea (OSA), but suffers significantly from poor patient adherence. This paper reports the three-year outcomes of a prospective multicentre cohort study examining the effect of hypoglossal...

Otolith dysfunction in congenitally deaf adults

This paper helps to further define the profile of ocular and cervical vestibular-evoked myogenic potentials (o and c VEMPs) in patients with congenital profound sensorineural hearing loss (PSHL). It highlights the prevalence of otolith (saccular and utricular) dysfunction that exists...

Neurological complications associated with managing degenerative cervical myelopathy

Degenerative cervical myelopathy (DCM) is a common neuropathologic status due to degenerative changes to the cervical spine. There are multiple operative techniques available, including anterior cervical discectomy and fusion, anterior cervical corpectomy, laminoplasty, laminectomy and laminectomy with fusion. C5 palsy...

NSC- HHT – a systematic review of intranasal Bevacizumab

This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...

The benefits of early voice therapy for unilateral vocal cord paralysis

This retrospective review of voice outcomes following a diagnosis of unilateral vocal fold paralysis divided patients into three groups according to the time of initiation of voice therapy following the onset of paralysis. The ‘early’ group started voice therapy within...

Chemo-radiation in elderly patients with head and neck cancers

Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...

Supplementing intranasal cortical steroids with montelukast: does it help?

Intranasal steroids are widely used in the treatment of allergic rhinitis. Whether or not the addition of montelukast helps was assessed in this study. This was a single centre prospective randomised double-blind placebo-controlled trial of two groups of patients, one...

Valsalva manoeuvre treatment of otitis media with effusion in adults

Otitis media with effusion (OME) is common in children but has a low prevalence in adults. There is some evidence to advocate middle ear inflation as a successful treatment for children with OME. This form of treatment is also recommended...