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CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Paediatric idiopathic sudden sensorineural hearing loss
This Turkish retrospective study looked at the radiological and clinical characteristics, prognostic factors and treatment outcomes in children diagnosed with idiopathic sudden sensorineural hearing loss (ISSNHL). Forty-eight children were included over an eight-year period. Complete recovery (CR) was achieved in...Mind the gap – developing a sustainable pipeline for hearing therapeutics
In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...Oral Tissue Collaborative Symposium
Building Excellence in Oral Tissue Biobanking
The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...European Laryngological Society (ELS) meets British Laryngological Association (BLA)
The meeting of the European Laryngological Society in May is being held in London, and is co-hosted by the British Laryngological Association. The President of the ELS, Ricard Simo, and the Secretary of the BLA, Declan Costello, exchanged thoughts about...
Steroid use in acute acoustic trauma
Acute acoustic trauma (AAT) injuries include noise-induced damage to inner and middle ear presenting as hearing loss, tinnitus and vertigo. Classic presentation is sensorineural hearing loss with an intact tympanic membrane. The authors carried out a case-control study in military...
Canopy: a medical translation app
Professional interpreters perform an integral role in the medical setting, ensuring that clinician-patient interactions are understood from both sides. As essential as they are, however, we have all experienced scenarios where we have been left, to our own devices, so...
Can amplification preserve auditory function?
Hearing loss is a noted modifiable risk factor for dementia, and is also associated with depression, decreased quality of life and isolation. Hearing aids are the main intervention for presbycusis and a 2017 Cochrane Review showed that they have a...BAAP End Year Symposium on Vestibular Compensation
Dr Sandarva Giri, ST4 Registrar in Audiovestibular Medicine, Lancashire Teaching Hospitals NHS Foundation Trust Dr Sabarinath Vijaykumar, ST5 Registrar in Audiovestibular Medicine, Royal Derby Hospital. Registration opened with participants joining from across the UK and overseas, setting the stage for...
Binaural Interference: A Guide for Audiologists
This book details what binaural interference is, it looks at the basic principles of this topic and follows the research over the years that has gone into investigating what causes binaural interference. It makes for an interesting read, covering a...
