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Systemic steroid therapy for reduction of macrophage migration inhibition factor in the control of nasal polyposis
It is believed that macrophage migration inhibitory factor mediates inflammation by stimulating the release of other pro-inflammatory cytokines. The use of systemic steroids in control of nasal polyposis is an established treatment. In this study the authors have aimed at...CI music: seeking perfection, accepting reality
Having just read about the challenges cochlear implant technology and music appreciation present, the musician Richard Reed beautifully illustrates the realities of this patient journey. An old friend of mine is an ardent music fan, and completely tone deaf. Long...Where ART meets Science: The Silence You Can Hear
Some moments have a sound you don’t hear with your ears but feel with your entire being. The artwork DS21008 (200 cm x 120 cm) captures such a moment: a Sunday morning in Maastricht, where the river Maas reflects the...New bone anchored hearing implant reaches clinical milestone
A new implant for bone-conduction hearing, BCI (Bone Conduction Implant), has been developed by Bo Håkansson and his team of researchers at Chalmers University of Technology and Sahlgrenska University Hospital, both in Gothenburg, Sweden. Unlike most bone-conduction devices used today,...Controlled clinical trial results for FDA-approved tinnitus treatment device Lenire published in Nature Communications
Nature Communications has published the peer-reviewed results of Neuromod Devices’ TENT-A3 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A3) clinical trial for the first and only FDA-approved bimodal tinnitus treatment device, Lenire.
Can we predict risk of adverse events preoperatively in patients undergoing head and neck cancer surgery?
Ed’s Choice reviews a paper aiming to create a reliable index to predict postoperative outcomes in head and neck cancer patients. This interesting study identifies variables that may assist in risk assessing prospective surgical candidates. There have been a few...Central auditory changes in SNHL
Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...Oscar Wilde’s Final Irony
The celebrated writer and poet, Oscar Fingal O'Flahertie Wills Wilde was born on 16 October 1854 in Dublin. He distinguished himself as a classicist at Trinity College Dublin before, earning a scholarship to Oxford University, where he gained a double...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
Unilateral vocal cord mobility impairment and laryngopulmonary physiology
The concept of iatrogenic recurrent laryngeal nerve injury following thyroid surgery is often considered with respect to voice change but its potential impact on airway physiology has thus far not been evaluated. A cross-sectional observational study reviewed 21 patients with...
