You searched for "trial"

1375 results found

Pharmacologic treatment options for tinnitus

This article summarises potential medications that could be used to treat tinnitus and the evidence behind their use. Effective medications to eliminate tinnitus remain elusive but treatment could be divided into two broad categories: treatment to reduce perception of tinnitus...

Double layer graft in endoscopic tympanoplasty

This Turkish retrospective study looked at the success rates following endoscopic tympanoplasty using the double layer graft technique. This involves using a tragal cartilage and perichondrium composite graft and a separate perichondrial graft for closure of the perforation. The crescent...

Do ENT surgical patients need VTE prophylaxis?

In the UK, current NICE guidance for venous thromboembolism (VTE) prevention does not give specific advice about patients undergoing otolaryngology/head and neck surgery (OHNS). This systematic review provides up-to-date information based on available, although limited, evidence about the incidence of...

What can we tell about swallow physiology from a bedside clinical assessment?

Knowledge about swallowing physiology has greatly increased with the use of instrumental assessments such as videofluoroscopy (VFS). The authors of this paper performed an analysis of data obtained from 60 stroke patients who were assessed via a clinical swallow examination...

Contemporary UK experience of oropharyngeal transoral laser microsurgery

It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...

Impact of the updated cancer staging system on HPV-positive disease

The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...

The debate: endoscopic vs microscopic ear surgery – meta-analysis of outcomes

Although the endoscopic approach to ear surgery has become more common in clinical practice, the debate about its role versus the traditional microscopic approach continues in many ENT units. This meta-analysis from the Mount Sinai ENT department in New York...

Are we making progress on tinnitus?

One of the aspects of tinnitus that drew me into it becoming a major theme of my clinical and research work was how little work had been done when I began to see patients in the mid 1980s. This struck...

Prognostic factors for myringoplasty

This retrospective study looked at the factors that were associated with a higher success rate for tympanic membrane perforation closure. The authors looked at 247 procedures. They compared the results of temporalis fascia versus tragal cartilage. The cartilage grafts had...

Management of postoperative cholesteatoma

This prospective longitudinal observational study compared the ability of second-look surgery with that of surveillance using serial non-echo-planar diffusion-weighted imaging to detect residual cholesteatoma after canal wall-up mastoidectomy. A total of 34 patients were included in the study who underwent...

Combined use of a hearing aid and a cochlear implant: a case study

When multi-channel cochlear implants (CIs) were first introduced in the 1980s, their use was restricted to people who derived no benefit from conventional amplification. Over the past three decades, however, the criteria for CIs has been relaxed considerably, and it...

Which graft is better for type 1 tympanoplasty in elderly patients?

Type 1 tympanoplasty is a procedure performed to repair tympanic membrane perforations, primarily to reduce otorrhoea. This may subsequently lead to improvement of hearing. The common graft materials used are temporalis fascia and cartilage from tragus or concha. The authors...