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Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

The use of botulinum toxin A to reverse paralysis of the lower lip

The aim of this retrospective case series was to examine the role of botulinum toxin A in paediatric patients with paralysis of the lower lip. Depressor or elevator muscles of the lip (unaffected side) were injected with varying doses of...

Advancing the tongue in OSA surgery

This article further delineates the options for hypopharyngeal OSA and describes the technique of genioglossus advancement to improve the tension in the tongue base. The authors take the reader through the relevant anatomy appropriate to the procedure and describe the...

The relevance of rhinoplasty and septorhinoplasty from the commissioners

The rising costs of running the National Health Service and its overburdened resources has led to the constant monitoring of the low clinical value treatments. The operations of rhinoplasty and septorhinoplasty inevitably fall into this group and are subject to...

mAXIS stapes prosthesis

Since Shea’s first description of stapes mobilisation procedure, improvements in the technique have resulted in the development of alloplastic stapes prosthesis. The authors prospectively conducted a single-centre study to determine the safety and efficacy of the MED-EL mAXIS stapes prosthesis...

Frozen sections; a systematic review

This systematic review and meta-analysis looked at 5 studies assessing the impact of intraoperative frozen section analysis on final margin status, locoregional recurrence and survival in patients with an oral squamous cell carcinoma. The analysis showed no significant difference in...

Sleep Disordered Breathing in Children: A Comprehensive Clinical Guide to Evaluation and Treatment

This book offers a very comprehensive guide to sleep disorders in childhood. It is presented in six sections covering the normal upper airway, sleep during development, diagnostic assessment of sleep and breathing in children, sleep disordered breathing in children, the...

Oral Complications of Cancer and its Management

The title of this book had the promise to lead us to a clear understanding of the common complications associated with surgical and nonsurgical interventions for oral cancers; and, of course, tell us about the evidence based management of its...

Handbook of Otolaryngic Allergy

This book is an excellent companion for doctors dealing with allergy and rhinological complications of allergy. It contains detailed information of immunological pathways, from cells to systemic effects, of cellular reaction. It is well organised and takes the reader through...

Common skin conditions of the ear and how best to manage them

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Voice change after total thyroidectomy with intact laryngeal nerves – a common but temporary problem

It has been reported that up to 87% of patients have a degree of voice dysfunction after thyroidectomy, even when the laryngeal nerves are preserved. Postoperative inflammation, laryngeal oedema due to vascular congestion, direct damage to the cricothyroid muscles and...

Suspect the unsuspecting in thyroid cancer

This article reminds readers of how often invasive thyroid disease can appear, as the symptomatology is minimal. Noticeable airway symptoms appear after 50% of the airway is involved and surgeons can often fall in the unsuspecting trap of discovering locally...