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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
A useful adjuvant treatment for SNAC or IP
5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...An undergraduate perspective on changes to audiology education
I have completed two years of study and am currently preparing for my final year, which consists of a twenty-five week placement alongside a research project and theoretical modules. It is inevitable that, as a result of the changes made...Monitored safe medical practice: minimising patient harm will reduce medical negligence bill for the NHS
Patrick Bradley ruminates on a celebrated career in ENT head and neck surgery and suggests that increasing the possibility of positive outcomes to contemporary patient safety initiatives by the NHS must involve efforts to develop an enthusiastic contented workforce willing...
Patients with severe uncontrolled CRSwNP respond to biologics in the real world
Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...Changing perceptions in head and neck cancer management caused by quality of life issues
Sir Felix Semon was an outstanding clinician and exceptional laryngologist. The money raised by donations from his colleagues on his retirement in 1909 was used to establish the London University’s Semon Lecture. Semon’s Obituary in the BMJ, reads: “In Semon's...How to deliver bad news better
Delivering bad news well takes experience and time. The Ida team recommend the SPIKES protocol; providing structure for relaying bad news, giving confidence to those delivering it, and leaving recipients feeling cared for and informed. It’s among the most distressing...Widex UK & Ireland partner with Anglia Ruskin University
Widex UK & Ireland and Anglia Ruskin University (ARU) announced in July, an exciting project designed to create added value for independent hearing care professionals and future audiology graduates within the UK & Ireland.Are you sitting comfortably? Then we shall begin
Paediatric Audiologist, Natalie Stephenson, shares her experience working with children and young people, the impact of lockdown and the value of patient-centred care, throughout the COVID-19 pandemic. Am I glad that I know The Gruffalo off by heart? Yes, I...AUDIOLOGY - In conversation with Hans Henrik Philipsen
So your background is in social research, how did you develop an interest in this area? I have always had an immense curiosity when it comes to understanding other people and other cultures. My early experience as a teenager in...
