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The Laryngeal Pacemaker – developing an innovative solution for bilateral vocal fold paralysis
Bilateral vocal fold paralysis is a difficult condition to manage, with surgical interventions previously limited to tracheostomy or arytenoidectomy. Re-innervation surgery has been developed and, in recent years, a Laryngeal Pacemaker is now in clinical trials. We speak to two...The Laryngeal Pacemaker – developing an innovative solution for bilateral vocal fold paralysis
Bilateral vocal fold paralysis is a difficult condition to manage, with surgical interventions previously limited to tracheostomy or arytenoidectomy. Re-innervation surgery has been developed and, in recent years, a Laryngeal Pacemaker is now in clinical trials. We speak to two...
Narrow band imaging improves diagnosis of malignant laryngeal lesions
The manufacturers of narrow band imaging (NBI) claim better visualisation of mucosal abnormalities when compared with simple white light. The primary aim of the study was to compare the diagnostic accuracy of NBI and white light to diagnose malignant laryngeal...
Can laryngeal sensitivity testing predict aspiration and pneumonia in dysphagic patients?
The laryngeal adductor reflex (LAR) is characterised by brief vocal cord closure in response to laryngeal stimulation. It is important in swallowing physiology as it represents a mechanism for airway protection. The authors of this study examined whether the absence...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
Factors influencing transformation of laryngeal dysplasia to malignancy in a 10-year review
Laryngeal dysplasia has a propensity to change into malignancy, the generally reported rate of this being about 14%. In this retrospective study of 125 patients, the authors have assessed the severity of dysplasia in relation to the incidence and time...
Should we reconsider induction chemotherapy in advanced stage laryngeal cancer?
Use of chemo-radiotherapy for advanced laryngeal cancer led to a major shift in treatment as an alternative to total laryngectomy. Despite widespread adoption of chemoradiotherapy, survival rates have not improved and the original premise of matching neoadjuvant chemotherapy tumour response...
Are organ-preserving treatment strategies for T3 laryngeal cancers reducing patient survival?
This article presents the 10-year results of a single institution’s treatment of advanced laryngeal cancer. The institution established a protocol based on the Dutch Head and Neck Society consensus document on laryngeal cancer diagnostics and treatment published in 1991. This...
Combination PPI and intralesional steroid treatment for recurrent laryngeal granuloma
The existence of a wide range of treatments for recurrent laryngeal granulomas (repeat surgery, high-dose proton pump inhibitor (PPIs), surgery with botulinum toxin injection, botulinum toxin injection alone, etc) is a testament to the refractory nature of this condition, with...
In the West of Scotland, what factors impact and what are the survival trends for laryngeal cancer?
The TV and radio presenter Jamie Theakston recently returned to his radio show to announce he is cancer free. He had been off air for a year after having surgery to treat early-stage laryngeal cancer. His diagnosis was made when...
