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Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

19th Annual National ENT Masterclass®

Miss Eleanor Crossley, Association of Otolaryngologists in Training (AOT) President and ENT Registrar, South London DeaneryDoncaster Royal Infirmary was again the home of the 19th International ENT Masterclass in January 2025. The three-day programme was packed with sub-specialists and delegates...

In conversation with Professor Paul J Donald

Prof Paul J Donald has recently stepped down as Chairman of the ORL-HN Department at UC Davis in Sacramento and is winding down to retirement. In this interview with Prof Pat Bradley, Prof Donald explains some of the highlights of...

Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?

A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...

The Ewings and paediatric audiology

Medical historian, Laura Dawes, discusses how Irene and Alexander Ewing were instrumental in shaping paediatric audiology in the first half of the 20th century. Irene and Alexander Ewing were the power couple of audiology in the UK in the mid-20th...

Endoscopic airway interventions in children

Open surgery for paediatric airway pathologies such as subglottic stenosis was hailed as revolutionary when many of today’s paediatric ORL specialists were in training. Equipment, facilities and training has moved on and the high-quality optics in modern endoscopes, coupled with...

Psychogenic vestibular disorders: understanding and management

‘Psychogenic vestibular disorders’, also known as ‘functional vertigo and dizziness’, are common causes of dizziness and balance difficulty. Although our understanding of their underlying pathophysiology remains incomplete, Drs Diego Kaski and Amy Edwards outline how early identification and positive diagnosis...

Not just the scissors: the story of Myron Metzenbaum

Myron Metzenbaum was born in Cleveland, Ohio (USA) in 1876, the fourth of nine children. As a young man, he worked in the family’s linen store, where his father was well known to be very kind to the less fortunate...

Cochlear implantation techniques

This issue concentrates on the advancement in techniques within the field of implant otology starting with cochlear implantation. Here it is sub-divided into indications, candidacy (including full pre-operative testing and investigations), surgical technique and outcomes for both adults and children....

The preventative audiologist

Rob Shepheard has been championing the role of ‘the preventative audiologist’ for many years. In this article, he explores how that can be achieved.

The common frontal sinusotomy (Lothrop) and chronic rhinosinusitis

As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...

Transnasal endoscopic orbital decompression

Surgery for the eye complications of Grave’s disease is an area that, over the years, ENT has become more and more involved in due to our ability to access the orbit endoscopically. In this article, the authors describe their technique...