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Endotypes in chronic rhinosinusitis: clinical relevance
Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...
Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
Steroids for vocal cord mucus retention cysts
This is an interesting paper that describes the use of intralesional steroid injections to treat vocal cord mucus retention cysts. The gold standard is microlaryngoscopy and excision of the lesion. In patients who may be unable to undergo surgery, this...
Your voice and your personality
Variations of vocal effort are a normal adaptation to difficult communication situations. However, persistence of these abnormal strategies can lead to various functional dysphonias. In this experiment, the authors tested 41 females aged 18-52. The subjects were asked to instruct...
Vestibulo-ocular reflex and postural control in deaf children
The authors evaluated the impact of canal paresis detected by video head impulse test (vHIT) on postural control tested by platform posturography in children with sensorineural hearing loss. The study included 55 children (4-16 years old) with variable degrees of...Fifteen years of vestibular implant research in humans
Implants: it’s all in the balance! Prof Guyot and his team give us an update on their research in addressing bilateral vestibular deficits via an implant. Doctors are often unaware that people, even young, may lose vestibular function on both...General overview of endoscopic ear surgery: advantages and principles
The philosophy of endoscopic ear surgery presents surgeons with a tricky concept – does the magnificent view make up for the fact I need to operate with one hand? In this article, Jane Lea discusses the advantages of operating transcanal...
