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Clinical evaluation of an image-guided cochlear implant programming strategy
This study ingeniously combines two current areas of active research in cochlear implantation (CI), the first is the use of imaging to assess intra-cochlear electrode position. The second, is the optimisation of a programming strategy to prevent current spread between...
Differences between paediatric and adult cholesteatomas
An understanding of the differences between adult and paediatric cholesteatomas should be helpful in more effective management of the disease in children. In this study, the authors focused their comparison between paediatric and adult cholesteatomas to the operative findings, rates...
Understanding osseointegration for the otologist
Bone conduction implants are hearing devices that require osseointegration to create a stable and reliable interface between the hearing device and the skull to deliver sound to the cochlea. This article reviews the physiology of osseointegration, factors that may lead...
Chronic rhinitis endotypes
Chronic rhinitis (CR) is common with up to 30% of the population affected, with a significant impact on quality of life. CR includes several phenotypes with different pathogenesis including allergy, autoimmune, age, occupation, pregnancy, neurogenic and drugs. Such variation means...
Promising surgical technique for pulsatile tinnitus caused by sigmoid sinus dehiscence?
Pulsatile tinnitus (PT) can be caused by sigmoid sinus dehiscence (SSD). The authors report the results of 17 patients who underwent sandwich surgical technique for sigmoid sinus (SS) wall reconstruction for the treatment of pulsatile tinnitus caused by sigmoid sinus...
COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?
COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...
The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
Genetics of IP-III
The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...
