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Metformin, the magical solution!
Both noise-induced hearing loss (NIHL) and vestibular schwannomas (VSs) pose a challenge in terms of management. Metformin was suggested as a potential therapeutic drug for NIHL when the drug-target interaction data was investigated. Additionally, there are studies which demonstrate reduction...High intensity, high impact: tackling waiting lists one HIT at a time
A monthly high intensity theatre list in Sheffield shows how smart planning, teamwork and focus can dramatically reduce long ENT waiting lists. Finally, after many years of training, I’ve started my first consultant post – only to become part of...A brief history of adenoidectomy - a glowing report of the post nasal space
The traditional adenoid curette more closely resembles a medieval torture device than an instrument of cure. Therefore it is not much of a surprise to learn that it has changed little since its invention almost 150 years ago. During that...Does diet have a role in the prevention of tinnitus?
Tinnitus, diet and healthy ageing Despite the high prevalence of tinnitus, its exact aetiology remains unclear. Research has explored the role of various biological pathways in the development of tinnitus including age-related changes in the auditory system, impaired vascular function,...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...
Microsurgical trainees to avoid strenuous exercises?
It is commonly believed among microsurgeons that over-exertion can impair microsurgical performance. The authors aimed to investigate if they could prove this theory and compared the performance of medical students, postgraduate trainees and expert controls who were microsurgery tutors. A...
Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017
Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...
Does cholesteatoma surgery affect school performance?
While much focus has been placed on short-term complications associated with cholesteatoma, a lack of knowledge remains about the impact suffering from cholesteatoma in childhood may have on educational outcome. The aim of the study was to investigate whether suffering...
Transnasal oesophagoscopy in head and neck cancer: an update
The role of transnasal oesophagoscopy (TNE) in the management of head and neck cancer patients is evolving. Until 1990, oesphagoscopy required specialist endoscopists, general anaesthesia or sedation. This review succinctly summarises updates in the evidence for TNE in: i) Screening...
From a dysphagia clinical trial to a multidisciplinary head and neck clinical pathway – the road to implementation
This paper describes the barriers and facilitators to establishing a structured and coordinated multidisciplinary care pathway for patients with head and neck cancer at a medical centre in the USA. The initiative was set in motion by the roll out...
A trial of house dust mite sublingual tablet in children with allergic rhinitis
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...
