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OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
NSC- HHT – a systematic review of intranasal Bevacizumab
This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...
Reflux, a pre-disposing factor in paediatric OME?
It is almost 20 years since the Lancet publication by Tasker et al describing gastric juice in the glue ear of children. This paper attempts to look at the body of literature which has focused specifically on the clinical association...
Reducing the risk of Frey’s syndrome after parotidectomy – which methods are best?
Gustatory sweating or Frey’s syndrome is a well-recognised complication of parotid surgery. The reported incidence is highly variable, from 4% to 96%, with around 30% of patients reporting symptoms. A number of intraoperative techniques can be used to reduce the...
The use of repositioning chairs in the diagnosis and treatment of BPPV
The authors performed a systematic review assessing the utilisation of multi-axial repositioning chairs, such as the TRV chair and the Epley Omniax Rotator, in the diagnosis and treatment of BPPV. They reviewed nine studies, of which four were prospective studies....
Prognostic value of vascular ultrasonographic findings in patients with idiopathic sudden sensorineural hearing loss
Sudden sensorineural hearing loss is often idiopathic. Although the aetiology of idiopathic sudden sensorineural hearing loss (ISSNHL) is unclear, vascular compromise is one of the frequently proposed hypotheses to explain its pathophysiology. Existing studies have shown an association between ISSNHL...
Choosing instrumental assessments of swallowing for children
Swallowing disorders in children are increasingly common due to advances in medical care allowing them to survive prematurity or complex health conditions. Careful assessment of eating and drinking is necessary to ensure that children are managed both safely and with...
Auricular acupuncture for tinnitus
Acupuncture has long been suggested as a complementary option for tinnitus, but its effectiveness remains uncertain. This systematic review analysed 57 studies published between 1975 and 2023, drawn from an initial 167 identified. The studies were highly variable, ranging from...
Predicting aspiration pneumonia in adults
Aspiration occurs when oropharyngeal or gastric contents are inhaled into the larynx and lower respiratory tract. When the aspirated material is colonised by pathogenic microorganisms, this may result in aspiration pneumonia. In contrast, aspiration of sterile gastric contents may lead...In conversation with Rosaleen Shine
Rosaleen Shine is synonymous with ENT and Audiology News. She was a key member of the team that founded what was then ENT News 25 years ago, and is well known to ORL and audiology colleagues all over the globe....
