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Metformin, the magical solution!

Both noise-induced hearing loss (NIHL) and vestibular schwannomas (VSs) pose a challenge in terms of management. Metformin was suggested as a potential therapeutic drug for NIHL when the drug-target interaction data was investigated. Additionally, there are studies which demonstrate reduction...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Pediatric Dysphagia: Etiologies, Diagnosis, and Management

This book is an up-to-date and comprehensive textbook that gives an in-depth understanding and management of all aspects relating to dysphagia. Members of the interdisciplinary team at Cincinnati Children’s Hospital Medical Centre, who have an extensive experience in the management...

Inferior alveolar nerve recovery after ORIF fractured mandible

Mandibular fractures are quite common facial injuries, but aetiology varies with country and age. Common treatment options are open reduction and internal fixation via an intra-oral or extra-oral incision. Nerve injury or dysfunction is often seen preoperatively and may also...

Hearing intervention to prevent dementia

People with hearing impairment have an increased risk of incident all-cause dementia proportional to the severity of loss compared to those with normal hearing. Treating hearing impairment may therefore serve to slow or prevent the onset of cognitive decline. This...

Surgical options for children with OSA

This paper looks at the surgical management of OSA in children and approaches the method of patient selection initially. They discuss the role of polysomnography in that it is part of the AAOHNS criteria in those patients with OSA symptoms...

Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

The future of treatments for hearing and balance: a 15 and 50-year perspective

Jameel Muzaffar and Manohar Bance paint a picture of what otology will look like 15 and 50 years’ time. Will we still need doctors? Will there still be an ENT news journal? The last 50 years have seen advances including...

A dizzying response to the silent killer

In this recent case control report by Kandemir and colleagues, we are asked to consider the association between hypertensive disease and hearing impairment, tinnitus and dizziness. A 200-strong cohort of normotensive and newly-diagnosed hypertensive patients underwent pure tone audiometry, Tinnitus...

Neuromod closes €10 million financing to accelerate commercialisation

Neuromod, an Irish medical device company specialising in tinnitus, has closed a €10 million equity financing deal in a Series B fundraising expansion to expand the availability of tinnitus treatment device, Lenire. Financing was oversubscribed and led by existing investors...

Developing outcome measures for research

There are challenges in developing outcomes measures; Professor Hall presents five top pointers for making rapid progress in developing outcome measures for research purposes. Anyone who has worked clinically with hearing loss will appreciate that every patient’s experience is personal....