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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
DVT prophylaxis in cranial procedures
Deep vein thrombosis (DVT) is a result of disturbed balances in blood flow patterns, blood clotting factors promoting coagulation and vessel wall endothelial injury. The subsequent disruption of coagulation and fibrinolysis mechanisms lead to venous clot formation and propagation. The...
The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...When dinosaurs ruled the earth
Optimism is abundant in medical research, but frequently ends up being tempered with reality. In his inimitable style, Chris Potter looks back over his career – starting with his medical school memories of Bentley-driving ENT consultants, and moving forward through...Microneedles enable inner ear precision medicine
Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...Face to Face – facial reconstructive surgery mission in Ukraine
Face to Face is a humanitarian project to help those who have suffered facial trauma as a result of Russia's war against Ukraine.BMLA 2023 Annual Conference & Educational Courses
Navroz Singh (far right) with Nirmal and Vasant Oswal (second and third left) and the other recipients of the Vasant and Nirmal Oswal Trainee Scholarship. Navroz Singh, core surgical trainee at Kings College NHS Trust. This year’s British Medical Laser...BMLA Annual Conference & Educational Courses
Navroz Singh, core surgical trainee at Kings College NHS Trust. This year’s British Medical Laser Association (BMLA) annual conference was held over three days in a beautiful venue overlooking a sunny Cardiff Bay. It was attended by individuals hailing from...
Dirty Work
Gabriel Weston’s new novel chronicles four traumatic weeks in the life of its narrator, Dr Nancy Mullion. Nancy is a young trainee in obstetrics and gynaecology, the subject of a General Medical Council (GMC) investigation into her clinical performance following...Lessons learned from running a national thyroid surgery registry
The UK Registry of Endocrine and Thyroid Surgery is now yielding the rewards of meticulous data collection and years of hard work. David Scott-Coombes discusses the advantages and the unintended consequences of their success. The British Association of Endocrine and...In search of courage; transition into Army
In search of courage. Well, that is how it all started. I was fairly advanced in surgical training not to mention age, when I decided to join the Territorial Army (TA). My peers, on hearing this couldn’t decide whether I...
