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Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

4th Annual Inner Ear Disorders Therapeutics Summit

Terrri Gaskell, Chief Technology Officer, Rinri TherapueticsHeld in Boston, USA, this was an essential gathering that captured the growing excitement in both the biotech and clinical communities surrounding the rapid advancements in hearing loss therapies. With the potential to significantly...

Vestibular functions of hereditary hearing loss patients with GJB2 mutations

Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...

A higher aspiration for fine needles

Fine needle aspiration biopsy (FNAB) has aided in the diagnosis and management of thyroid nodules for decades. Now a rapid evolution is hoped to benefit an increasing cohort of patients with small nodules and non-diagnostic investigations. This review discusses the...

Childhood bony facial tumours

This review article covering maxillary and mandibular tumours is from an edition of the Clinics covering paediatric head and neck masses from frequently encountered congenital malformations to the rarities. There is a wide differential diagnosis for childhood mandibular or maxillary...

Those little friends in our noses

Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...

Age and sleep disorders as risk factors for Ménière’s disease

Decades after it was first described, the pathophysiology of Ménière’s disease is still a subject for research and discussion, with several controversies regarding its management. Several factors have been reported to cause Ménière’s disease including viral infections, allergies, genetic factors,...

BAPO Annual Meeting 2025

BAPO’s flagship annual meeting returns for 2025 in Glasgow!Haytham Kubba extends his warm invitation to this exciting gathering, where Professor Natalie Loundon from Hôpital Necker-Enfants Malades, Paris, will deliver the prestigious John Evans Lecture on gene therapy in paediatric hearing...

5th Annual Inner Ear Disorders Therapeutics Summit

Coined by industry as the only meeting of its kind and uniquely positioned to share fresh ideas and assess viable approaches to your most pressing preclinical, translational, and clinical bottlenecks, the 5th Inner Ear Disorders Summit returns as a forum to benchmark learnings from past failures, reignite momentum and develop investment into the audiology therapeutic landscape.

In conversation with Professor Eugene Myers: My life in ENT

In a series of interviews, former Chairman of the Editorial Board for ENT & audiology news, Professor Patrick J Bradley, speaks with eminent otolaryngologists who have retired (or are about to retire) from practice. Our first is with Professor Gene...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...