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Pomegranate juice as an otoprotective agent
Chemotherapeutic agents such as cisplatin, given alongside irradiation, offer a survival advantage in head and neck cancer. Some patients often complain bitterly about side-effects of their treatment, one of which is ototoxicity. In this paper, the authors propose the use...
Elevated prevalence of late-onset dysphagia among head and neck cancer survivors and identifying risk factors
Dysphagia is one of the most common problems affecting head and neck cancer (HNC) survivors. There are few studies investigating late-onset dysphagia post-treatment. The authors set out to investigate the prevalence of dysphagia-related diagnoses and procedures five years’ post-treatment, changes...
Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma
Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...
Thyroidectomy patient survey regarding voice outcomes
One of the common adverse effects following thyroid surgery is a change in voice, which may be related to iatrogenic injury to the recurrent laryngeal nerve or superior laryngeal nerve during surgery or by direct cancer involvement. The burden of...
Predicting the need for salvage laryngectomy
The treatment of laryngeal cancer has seen a shift towards organ preservation strategies with non-surgical treatment offering equivalent survival outcomes. Nonetheless, salvage total laryngectomy (SLT) remains an important curative management option in cases of treatment failure or recurrence. The authors...Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy
Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...
Adjuvant radiotherapy for locally advanced (T3–4) major salivary gland cancer – survival benefits quantified
Complete surgical excision of major salivary gland cancers (MSGCs) is the current mainstay of curative treatment for this disease. Indications for postoperative radiotherapy according to current UK national guidelines include high-grade tumours, advanced-stage (stage 3–4) tumours, involved resection margins, perineural...
