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New aminoglycosides with reduced ototoxicity risk

Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...

Patient-reported outcome measures in septorhinoplasty

Patient-reported outcome measures (PROMs) are used increasingly in surgical research to quantify the efficacy of surgical interventions. This can help to fill an ‘evidence gap’ where healthcare rationing threatens particular treatments. Procedures aimed at improving quality of life, especially with...

BAHA loading two weeks after implant insertion

The time thought necessary for sufficient osseointegration to occur to enable use of a BAHA has reduced from months to a few weeks. This paper further reduces this timescale to two weeks in patients with healthy bone and soft tissue...

Auditory brainstem response patterns are neural signatures

Through examples, this article describes how particular aspects of auditory brainstem responses can portray certain kinds of language or communication impairments – a characteristic pattern or ‘neural signature’. A reduction in processing of the fundamental frequency is seen commonly in...

Earplug use in clubbers

Past studies show that there is a low frequency of use of earplugs at music events. In this research article produced by the National Acoustic Laboratories, Australia, a group of 51 regular attendees at music events were recruited and given...

Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Anatomy revision

This article is well-received as an article that goes into appropriate length and depth regarding the embryology and subsequent growth of the paediatric nose (internal and external), nasopharynx and all of the individual sinuses. It has excellent line diagrams of...

How can we assess children with complex needs?

In the early days of cochlear implantation, children with additional disorders were being excluded as poor candidates whereas today a large number of children with complex needs are being referred for cochlear implant assessment. However, the related problems include difficulties...

Zinc and rhinosinusitis

Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...

Are elective neck dissections needed during salvage laryngectomy?

There has recently been a move away from elective neck dissections in the setting of salvage laryngectomy. This has mainly resulted from an appreciation of the increase in morbidity, in particular pharyngocutaneous fistula formation, and an improvement in cross-sectional imaging...

Planning for the long term when working with young people with TBI

Traumatic brain injuries are most common amongst young people and can have long term consequences. The authors of this article provide an approach to management of cognitive and communication difficulties which starts with a detailed assessment using the model of...

How long is too long? Waiting times for speech and language therapy

Waiting lists are a reality of clinical practice, and many health and social care professionals become used to having to cope with this. The authors of this paper addressed this issue by examining written submissions to the 2014 Senate Inquiry...