You searched for "trial"

1439 results found

ICG in ENT surgery

The use of fluorescence imaging is well established in the medical sphere, forming an essential arm of medical diagnostics with liver function, ophthalmic angiography, and assessment in cell biology with fluorescence microscopy. Fluorescence imaging in surgery, however, is an evolving...

Lancet Commission on Hearing Loss

The Lancet Commission on Hearing Loss was convened in 2019, and its main report will be published in 2023. We learn more about it here. The Lancet Commission on Hearing Loss was convened in 2019, and was charged by Richard...

Jarrod Homer and Stuart Winter: Development of the sixth edition of the UK multidisciplinary head and neck cancer guidelines

Head and neck cancer care is a complex and constantly evolving field. What’s new and how are national guidelines on the subject produced? We spoke to Professors Homer and Winter, the lead authors of the most recent edition of the...

COOL therapy for cisplatin-induced hearing loss

Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...

Jarrod Homer and Stuart Winter: Development of the sixth edition of the UK multidisciplinary head and neck cancer guidelines

Head and neck cancer care is a complex and constantly evolving field. What’s new and how are national guidelines on the subject produced? We spoke to Professors Homer and Winter, the lead authors of the most recent edition of the...

Bettear: one start-up’s journey to bridging a technological gap in pursuit of auditory accessibility

Imagine your disappointment if you have been looking forward to seeing your favourite grunge band play live at the Dog and Duck for weeks. Your family is bored of you constantly playing their greatest hits. But when you turn up...

Body self-image – the ENT perspective

Body dysmorphic disorder is a serious psychiatric condition that we all need to be aware of when contemplating aesthetic surgery. It can present in children as well as adults. Prof Vieira and Dr de Carvalho discuss the tell-tale signs and...

High dose betahistine as effective as, but slower acting compared to intratympanic dexamethasone in intractable Meniere’s disease

The management of intractable Meniere’s disease poses a complex conundrum to otolaryngologists. The focus of treatment is decreasing the severity and frequency of vertigo and tinnitus whilst trying to preserve hearing. Betahistine has been used for many years in the...

Consider PCR testing in culture negative necrotising otitis externa

Necrotising otitis externa (NOE) often does not yield identification of a causative organism to treat although in 90% of cases it is a member of the pseudomonas species. The incidence of fungal NOE is not to be forgotten and this...

Corticosteroid prescribing in ENT - are we at risk of being sued?

Of medications leading to malpractice claims, corticosteroids comprise the third most common. They are used widely and have a significant side-effect profile: hypertension, lipodystrophy, diabetes, avascular necrosis of the femoral head, peptic ulceration and psychiatric reactions to name but a...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Does vocal tremor lead to changes in swallowing function?

Vocal tremor (VT) is a debilitating problem, but remains challenging to treat. Its pathophysiology remains indeterminate and there is a lack of consensus on phenotypes. Clinically, VT is often noted to be present in muscles outside of the larynx, including...