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2226 results found

COOL therapy for cisplatin-induced hearing loss

Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...

Hidden hearing loss in humans

Awareness of cochlear synaptopathy (‘hidden hearing loss’) is growing. Chris Plack gives us an introduction to the condition, defining it and reviewing recent research in humans and animals with respect to noise exposure. The main cause of hearing loss is...

COVID vaccination and its relation to Bell’s palsy

The SARS-CoV-2 virus outbreak in 2020 continues to be investigated as well as its after-effects on those infected by it. The vaccines created for the public were groundbreaking achievements, evidenced by the lives saved by them and the return to...

Preoperative CT checklist (using the ‘CLOSE’ mnemonic) improves identification of anatomical variants for endoscopic sinus surgery

Computed tomography (CT) scans of the paranasal sinuses act as roadmaps for endoscopic sinus surgery (ESS) and careful inspection preoperatively warns the operating surgeon of critical anatomical variants. This study aimed to investigate if implementation of a pre-ESS CT checklist...

Damage to the cochlear nucleus with electrocautery to the cochlear nerve

This study is of importance to neurotologists and neurosurgeons. It is unclear why patients with NF2 have poorer outcomes with an auditory brainstem implant compared to non-tumour patients. This effect is postulated to be due to damage to certain cells...

Platelet-rich plasma to reduce post-tonsillectomy haemorrhage and pain

Minimising haemorrhage and promoting healing of raw areas are cornerstones for uneventful and speedy recovery after tonsillectomy. In this single-blinded prospective experimental study, application of platelet-rich plasma to one side tonsillar bed has been compared to the other side in...

Are you still talking about Covid?

Bell’s palsy (idiopathic facial nerve palsy) has an annual incidence of 15 to 30 cases per 100,000 people. This study aims to assess the effect of Covid and Covid vaccination on this incidence using a large database. Authors used TriNetX,...

5th Annual Inner Ear Disorders Therapeutics Summit

Coined by industry as the only meeting of its kind and uniquely positioned to share fresh ideas and assess viable approaches to your most pressing preclinical, translational, and clinical bottlenecks, the 5th Inner Ear Disorders Summit returns as a forum to benchmark learnings from past failures, reignite momentum and develop investment into the audiology therapeutic landscape.

SCC of pinna – which histological features could predict prognosis?

Cutaneous squamous cell carcinoma (SCC) of the pinna is reported to have a higher rate of metastasis than cutaneous SCC originating from elsewhere - up to 16% compared with less than 2% for the latter. The authors aimed to assess...

In this issue...Inner Ear Therapeutics

Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Ralph Holme, Director of Research and Insight, RNID, UK. Ralph. E: Holme@rnid.org.uk W: www.rnid.org.uk For Mar/Apr 2022, we sang the...

Central auditory changes in SNHL

Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...

Biologics for deafness

Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....