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Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid

This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...

60th ENT Congress for the South African Society of ORL-OHNS

Dr Greta Niemann, ENT surgeon, Pretoria The 60th Annual ENT Conference held in Pretoria in November was a remarkable event, skilfully organised and offering an exceptional line-up of international and local speakers. This year’s gathering provided a unique opportunity for...

ECHNO 2025

Jonathan Fussey, Consultant ENT Head & Neck Surgeon, University Hospitals BirminghamThis year marked the 11th European Congress on Head and Neck Oncology, held in the impressive Beurs Van Berlage in the centre of Amsterdam. Delegates from around the world convened...

Further understanding of GJB2 hearing loss

For many years, hearing loss has been an area which has attracted the interest of clinical and academic geneticists. Genetic testing for severe-profound hearing loss is now commonplace in many healthcare systems. Understanding the genetics of hearing loss has improved...

QuietStar continues to set new standards in noise control

Working in partnership with a local main contractor, QuietStar recently finished a complete ISO-compliant paediatric audiology test room suite for St Helen’s House in Ipswich, UK, part of the West Suffolk NHS Foundation Trust.

Hilotherapy for facial surgery patients?

Hilotherapy involves administering regulated cold compression through a facemask. The principle of this treatment involves cyotherapy as a traditional treatment for reducing inflammation, pain and swelling following trauma. It is believed that using hilotherapy (Hilotherm®), which uses a mask to...

Salivary gland blues…

Intravenous methylene blue is a well-described method to assist in intraoperative localisation of parathyroid glands. The technique does come with challenges as anybody will know who has had to run adjacent to a theatre-bound trolley to ensure that the infusion...

A new hydrogel dural sealant for CSF repair

This paper reports the findings of a multicentre prospective randomised trial conducted to demonstrate the efficacy of the Adherus Dural Sealant for FDA approval. The Adherus Dural Sealant was compared with the control, DuraSeal Dural Sealant. It was applied to...

BioSpectrum Piezotome voted “Best Surgical Product of the Year 2021”

Voted “Best Surgical Product of the Year 2021” at the recent Aesthetic Awards, Piezotome is the number one choice for ultrasonic rhinoplasty in the UK and around the world.

Endoscopic excision of cholesteatoma

In this article Vikranth Visvanathan describes an exciting development on the use of endoscopic technology in complex otological practice. Transcanal endoscopic ear surgery (TEES) is rapidly evolving as a recognised method of addressing middle ear and mastoid pathology. Since its...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Random-pattern skin flaps: part 2 - rhomboid and bilobed flaps

In the second of our series on local skin flaps (see Part 1 here, Part 3 here and Part 4 here), the authors describe more techniques and examples of various skin flaps that trainees should find very interesting. Rhomboid flap...