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CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...
Intraoperative identification of primary tumours in unknown primary head and neck cancer using transoral laser microsurgery with frozen sections
The aim of the study was to compare the sensitivity and specificity of intraoperative identification of primary tumours in patients with unknown primary head and neck squamous cell carcinoma (UP HNSCC) using transoral laser microsurgery (TLM) with frozen sections, with...
Show me the video: modelling for behaviour change
It is estimated that 2% of people in the United States have autism. The DSM 5th edition defines the autism spectrum diagnosis criteria as when an individual has social communication difficulties, as well as restrictive and repetitive behaviours. One intervention...
Narrow band imaging in the management of carcinoma of unknown primary
This was a retrospective study to assess the utility of narrow band imaging (NBI) in the detection of a primary site in carcinoma of unknown primary (CUP). Patients with CUP who underwent transoral robotic surgery (TORS) and preoperative imaging with...
Quality of life after cochlear implantation in the older population
Cochlear implants (CI) have been increasingly adopted in older adults with severe to profound hearing loss as a result of the growing and ageing world population. There is much interest in the cost-effectiveness and quality of life in CI users....
Does septoplasty improve smell?
This is a study from Barcelona on a very interesting topic: does septoplasty change sense of smell? The theory being that a deviated septum would prevent airflow to the olfactory region and once the anatomical obstruction has been relieved, that...
When should revision FESS leave you reaching for the script pad?
This very interesting work from the professorial team in London seeks to define a group of patients with CRSwNP who may benefit from early biological treatment since they are at risk of failure of surgical and conventional medical management. Approximately...
The basis of auditory processing disorder: what can we learn from corticals?
Auditory processing disorder (APD) is a poorly understood, heterogenous and surprisingly common condition. It manifests as a perceptual difficulty in centrally processing auditory information. Diagnosis is usually based on a variety of behavioural tests involving verbal and non-verbal assessments. In...
Moving towards implanting children below 12 months of age
Newborn hearing screening has ensured that deaf infants are identified soon after birth so that habilitation can begin as early as possible. Cochlear implantation is a key component of early intervention for some children, but it is often not performed...
Persistent imbalance after traumatic brain injury is central in origin
Several residual symptoms, including dizziness and imbalance, can follow traumatic brain injury, no matter how mild. This study focused on the mechanisms, peripheral and central, underlying the complaint of persistent imbalance in patients with chronic mild traumatic brain injury (mTBI)....
Obstructive sleep apnoea in common vestibular disorders
The importance of getting a good night’s sleep is often acknowledged but may be particularly difficult to achieve for those with obstructive sleep apnoea (OSA). In addition to high blood pressure, increased risk of stroke and depression, balance problems may...
