You searched for "Genetic"

1574 results found

A novel graft material for endoscopic tympanoplasty using the pre-tragal SMAS layer

The traditional biological graft materials for providing a scaffold for tympanic membrane reconstruction include temporalis fascia as well as conchal and tragal perichondrium/cartilage. This group from Taiwan present a novel graft option using the superficial musculo-aponeurotic system (SMAS) layer. They...

Neuromodulation in drug resistant epilepsy

Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...

Managing hearing preservation expectations of adult CI patients

This paper is a single-centre review of adult cochlear implants in patients with preserved low-frequency hearing, focusing on the outcomes at 10 months post-implantation, and the rates of electroacoustic stimulation actually used in this group of patients. The centre identified...

Hidden disabilities and cochlear implantation under 12 months of age

There has been a global shift to providing children with severe-profound deafness cochlear implants (CIs) before they are 12 months old. Early intervention is critical and one of the overriding factors in successful outcomes for children with CIs. Early implantation...

Compress to suppress the venous tinnitus

This interesting retrospective case series analyses the effectiveness of a modified surgical technique with retromastoid reconstruction of the sigmoid sinus by mechanical compression with Surgicel and bone wax packing under local anaesthesia for patients with venous pulsatile tinnitus related to...

Combination PPI and intralesional steroid treatment for recurrent laryngeal granuloma

The existence of a wide range of treatments for recurrent laryngeal granulomas (repeat surgery, high-dose proton pump inhibitor (PPIs), surgery with botulinum toxin injection, botulinum toxin injection alone, etc) is a testament to the refractory nature of this condition, with...

Outcomes at three years post-implantation of the Bonebridge device

This is a MED-EL-funded study of the hearing outcomes and complication rates of the Bonebridge active transcutaneous bone conduction implant (BCI). The authors have declared no conflict of interest. Follow-up occurred at intervals for 36 months post-implantation in all 57...

How can we actually be culturally responsive?

Now, more than ever, we need to take action to meet the needs of the students and patients we work with. Black Lives Matter only emphasised how little progress has been made in this area to date. The authors of...

International consensus paper on implantable devices for conductive or mixed loss

This is a weighty but insightful ‘Special Feature’ paper in the June edition of Otology and Neurotology. It has the broad aim to gather current opinion from otologists, audiologists, manufacturers and health-economists from around the world on unilateral hearing implantation...

Does endoscopic sinus surgery for chronic rhinosinusitis improve COPD?

Chronic rhinosinusitis (CRS) can be associated with asthma, with a reported frequency of asthma in patients with CRS of up to 44%. COPD is another lung condition that can be associated with CRS. This longitudinal study reviewed the nasal and...

Impact of vestibular rehabilitation on patients with peripheral vestibular disorders

Vestibular rehabilitation is a widely used treatment for vestibular dysfunction. It can improve dizziness, fall risk, balance, and emotional status. However, some patients do not get benefit from vestibular rehabilitation. In this study, the authors assessed the impact of dizziness...

Sudden sensorineural hearing loss – who will get better?

Idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare but potentially devastating condition. For patients presenting with this condition, prognosis is of paramount importance. Wu et al begin to address this issue by retrospectively studying 17 potential prognostic factors for...