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The role of the maxillo-facial surgeon in the management of skull base malignancy
Whilst ablative surgery remains the principal treatment option for head and neck malignancy, the skull base is the last frontier. The complex anatomy, supreme functionality of the brain, and varied pathology provokes many a detailed discussion in the multidisciplinary team...OBITUARY: Prof Shanmugam Kameswaran (1923-2021)
Professor Shanmugam Kameswaran was born in 1923 and did his MBBS and MS at Madras Medical College, India, under PV Cherian who later became the Governor of Maharashtra, India. He worked as his assistant and left for the UK in...The astronomer’s nose: Tycho Brahe’s controversial prosthesis
Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....New Audio CARL and CARL Platform Released by AHead Simulations
AHead Simulations brings accessibility and affordability to education and research in hearing healthcare through their release of the All-New Audio CARL and Newly Updated CARL Platform.
eNOS and OME
The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
Risk factors for post laryngectomy fistula
This is a meta-analysis looking at the postoperative pharyngocutaneous fistula rates following total laryngectomy. The authors ended up with 34 studies with about 2500 patients. The most striking finding was that preoperative radiotherapy was a significant risk factor as well...
Which da Vinci surgical system? Novel flexible, single-port versus current multiport, rigid-arm robotic surgical system
The da Vinci robotic surgical system has transformed how oropharyngeal head and neck surgery can be delivered. The existing da Vinci Si model has challenges: the dimensions of this are larger than would be ideal for head and neck surgery...
Is non-allergic rhinitis as bad as allergic?
Non-allergic rhinitis (NAR) occurs when rhinitis symptoms are not associated with allergic, infective or anatomical reason. It is responsible for almost half of all cases of rhinitis and affects around 300 million worldwide. Assessing NAR patients’ quality of life (QoL)...
Tinnitus association with psychiatric and personality disorders
Tinnitus attracts large interest among researchers all over the world due to its negative psychological side-effects. This study aimed at investigating lifetime and current prevalence of psychiatric and personality disorders in patients with long-lasting and distressing tinnitus. Participants included 49...
Evidence for balloon eustachian tuboplasty
Balloon eustachian tuboplasty is an emerging intervention aimed at the management of eustachian tube dysfunction (ETD) and its sequelae. The authors acknowledge that ETD is a common but frequently ill-defined problem, with no well-established direct treatment. They performed a systematic...
