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2191 results found

Recurrent facial palsy

Recurrent facial palsy is relatively rare, and its clinical features are not well known. The authors set out to investigate this further by undertaking a retrospective study of patients with recurrent facial palsy over a 14-year period. Only Bell’s palsy...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Septal perforation healing

This Turkish animal-based study looked at the healing properties of Hypericum Oleum (HO, or St John’s wort) and Triticum vulgare (TV, or wheat germ oil) on nasal septal perforations in rats. Both HO and TV have wound healing properties and...

The search for the holy grail of rhinosinusitis: another step towards phenotyping in CRS wNP?

For many years, scientists and clinicians have been trying to understand the infinite variability within the term ‘rhinosinusitis’ using radiology, basic science, epidemiology and then using their insights to solve the riddle of management: how to explain why some patients...

Mobile phones to assess productivity in rhinitis

Uncontrolled and moderate to severe allergic rhinitis (AR) has significant negative impact on work productivity. Work Productivity and Activity Impairment Allergic Specific Questionnaire (WPAI:AS) used to measure that impact showed this. Work productivity seems to improve when AR is treated....

An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

Best timing for post-treatment PET-CT scans in head and neck cancer

Unfortunately we know that the recurrence rate for head and neck cancer can be high, up to 30-50% in some series. These recurrences tend to occur within the first two years following treatment. Optimal surveillance strategies to detect recurrences early...

Synchronous bilateral tonsil cancer

There is a long-standing debate regarding either unilateral or bilateral tonsillectomy for histological confirmation of tonsil cancer. Bilateral tonsillectomy is the standard of care in Denmark for proven or suspected tonsil carcinoma, and in the diagnostic work-up of the unknown...

Predictors of complications in patients undergoing oral cavity cancer surgery

Surgical management of oral cavity cancers is complex, frequently involving extensive resections and complicated reconstructions. Quantification of risk in an individual patient may allow surgeons to more effectively identify patients at higher risk of complications and develop strategies for prevention,...

Paediatric salivary gland tumours

This is a review article of a rare group of neoplasms that frequently present as painless preauricular mass in older children. There is a wide differential including first branchial arch abnormalities, inflammatory and granulomatous processes. Those masses that are painless,...

Patients with advanced oral cavity carcinoma are not candidates for the ‘organ preservation’ approach

The authors of this study, from the University of Michigan, evaluated the role of induction chemotherapy for patients with stages III and IV resectable oral squamous cell carcinoma. Nineteen patients were initially enrolled in the induction chemotherapy cohort. Patients with...