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2549 results found

Therapeutic ultrasound for tumours

This review article provides details about the potential applications of transcranial focused ultrasound (FUS), its mechanism of action and the studies that have set the basis for its use in neuro-oncology. FUS is an emerging modality of therapy for various...

Bilateral transposition lip flaps of central upper lip defects

This case series brilliantly explains a novel technique to repair central upper lip deformities at a Moh’s reconstruction referral practice. Most of the current treatment operations advocate a secondary surgery in order to fully restore the philtral columns and the...

How well are we managing epistaxis cases?

Epistaxis constitutes 34.5% of all emergency admissions to otolaryngology departments nation-wide. Presently there are no detailed consensus guidelines for this commonest emergency, and there is tremendous variation of practice. Quite often, non-ENT trained doctors manage this emergency. This paper reviews...

Managing the most common branchial arch anomaly

This article is a well written, helpful summary of the management of the most common branchial anomaly in children – the second. These are characterised as cysts, sinuses or tracts between the anterior border of sternocleidomastoid, coursing between the internal...

Sleep before and after nasal polyposis surgery

This prospective French study looked at the change in nasal symptoms related to sleep, in a questionnaire before and after nasal polyposis surgery. Sixty-three patients who underwent endoscopic sinus surgery completed the DyNaChron questionnaire before, at six weeks and at...

An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

Septal surgery made easy?

The injecting of the greater palatine canal has been documented for some time. The authors in this paper expand this to the more common procedure of the septoplasty. They summarise the pros and cons published regarding the technique in sinus...

Occupational hazards affecting otolaryngologists

This is a questionnaire survey which received responses from 323 clinicians practising otolaryngology. The grades ranged from consultants to junior doctors. It was noted that nearly half of these respondents suffered from some form of musculoskeletal pain and it highlights...

Management of the ear in cleft lip and palate

The management of patients with cleft lip and palate includes a focus on effective speech and language function. Poor eustachian tube function and middle ear dysfunction mean over 90% of children suffer from otitis media with effusion. This article provides...

Can obstructive snoring affect the snorer’s ears as well?

Patients with obstructive sleep apnoea (OSA) often show severe nasal obstruction, chronic sinusitis and/or a deficit of nasal mucociliary clearance with nasopharyngeal stagnation of secretions possibly predisposing to eustachian tube dysfunction (ETD). This clinical prospective study investigates ETD, nasal resistance...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...