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1446 results found

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

Rapid, non-invasive and differential diagnosis of laryngopharyngeal reflux

Laryngopharyngeal reflux (LPR) is a significant condition that frequently goes undiagnosed at a primary care level, resulting in patients being unnecessarily referred to secondary care with symptoms such as a sore throat, persistent cough, vocal problems and issues with swallowing.

Streamlining ENT pathways

Laryngopharyngeal reflux (LPR) may present with severe extra-gastrointestinal symptoms – including a persistent cough, vocal problems, asthma or difficulty swallowing – that can be incorrectly attributed to ENT problems because patients and GPs alike assume they stem from colds, allergies or over-using the voice.

Accurately diagnosing reflux to direct personalised treatment

Laryngopharyngeal reflux (LPR) frequently causes severe extra-gastrointestinal symptoms – such as a persistent cough, vocal problems, asthma or difficulty swallowing – that can be easily confused with a common cold and allergies.

Erasmus Darwin and the larynx – but why is it where it is and when?

Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...

The pioneers of endoscopy and the sword swallowers

Adolf Kussmaul drew inspiration from an unlikely source to further the development of endoscopy… The early pioneers of airway endoscopy and oesophagoscopy were bedevilled by two major and seemingly insurmountable problems. One was the paucity of light sources, with reliance...

Rhinology, Sofia and freedom

Our president-elect and host of the ERS2023 shares her love for ERS, rhinology in general, and Bulgaria. Let her invitation to experience the “freedom to breathe” inspire us all to visit Sophia and enjoy a great congress in a fantastic...

A binaural detection task that reveals deficits in listeners having ‘slight’ or ‘hidden’ hearing loss

The association of degraded binaural processing in adults with clinically defined ‘slight’ or ‘hidden’ high frequency hearing loss is of great interest to clinicians if it can be measured. Leslie R Bernstein and Constantine Trahiotis share their findings in measurements...

Understanding new and emerging categories of hearing devices

The hearing device landscape is rapidly changing, and what should be given, to whom, and why, are questions that many hearing healthcare professionals are asking. Brent Edwards discusses these questions and how consumer characteristics may influence their choice. In 2016,...

Recent advances in the diagnosis of silent reflux

The vexed topic of reflux always generates much discussion, particularly when it comes to testing. We hear about a non-invasive assay that is gaining in popularity. Voice disorders impact around four percent of the UK population and can significantly hamper...

Hearing screening during childhood using speech and sounds in noise

Although there is high prevalence of late-onset, progressive, and acquired hearing losses during childhood, these hearing losses can easily go undetected due to the lack of systematic hearing screening beyond newborn hearing screening. In this article, the authors share the...