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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
CRSwNP and smell – is it just the obstruction?
Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...
Imaging of the parathyroid glands in primary hyperparathyroidism: where do we stand?
Primary hyperparathyroidism (PHPT) refers to an intrinsic parathyroid gland abnormality that produces excessive secretion of parathyroid hormone. PHPT is diagnosed biochemically, and surgical excision of the abnormal parathyroid tissue represents the only definitive cure. Historically, the standard operative management of...
Sarcopenia and dysphagia in older community-dwelling adults
The prevalence of dysphagia in community-dwelling older adults is reported to be around 15%. Outside of common neurological causes such as stroke, Parkinson’s disease and dementia, recent studies have suggested that sarcopenia may be an independent risk factor for the...
Reliability of modified Dix-Hallpike test
Modifications of the Dix-Hallpike (DH) are sometimes necessary when the traditional DH is not feasible. The absence of any formal studies on modified DH was the idea behind this multicentre (three academic centres), prospective, randomised, single blinded and controlled clinical...
Does balloon tuboplasty work in the long term, and how can we measure outcomes?
There is much interest and debate at ENT conferences and within current literature about the role of balloon dilatation techniques for Eustachian tube dysfunction (ETD), a condition which we still only have limited understanding of, and which can be challenging...
Future practice: tele-rehabilitation in speech and language therapy
It is known that our population is ageing, resulting in an increase in the number of people living with progressive neurological conditions such as Parkinson’s disease. Health services endeavour to deliver specialist and personalised care to all these people, often...
Pharmacologic treatment options for tinnitus
This article summarises potential medications that could be used to treat tinnitus and the evidence behind their use. Effective medications to eliminate tinnitus remain elusive but treatment could be divided into two broad categories: treatment to reduce perception of tinnitus...
3D-printed temporal bone models - how good can they be?
In the era of increasingly difficult and expensive-to-come-by cadaveric temporal bones with which to practise drilling and learn the complex 3D anatomy of the temporal bone, decent alternatives would be welcome. McMillan et al report a prospective comparison study in...
Endoscopic stapes surgery - pearls and pitfalls
Endoscopic ear surgery has gained popularity in recent years with wide panoramic visualisation of the operative field one of its key strengths. This article summarises the approach, set-up and outcomes of patients undergoing endoscopic stapes surgery. A key step during...
Hyperbaric oxygen therapy a treatment for sudden sensorineural hearing loss
Cochlear ischaemia has been postulated as one of the potential aetiologies for sudden sensorineural hearing loss. Hence, increasing oxygen delivery to the cochlea by hyperbaric oxygen therapy has been explored as a potential treatment to reverse hearing loss. The authors...
