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The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...Discovery in the genetics of complex disease: Otitis media
Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...Old age is hard to swallow
This article takes us through the diagnosis and management of swallowing problems common in older age. As our global population continues to grow and live longer, dysphagia will continue to be a global problem which needs to be recognised, understood...
Hypoglossal stimulation for OSA
Continuous positive airway pressure (CPAP) is a highly effective treatment for moderate-to-severe obstructive sleep apnoea (OSA), but suffers significantly from poor patient adherence. This paper reports the three-year outcomes of a prospective multicentre cohort study examining the effect of hypoglossal...
What to do if adenotonsillectomy does not cure sleep apnoea in children?
This article reviews the management of children with persistent obstructive sleep apnoea (OSA) following adenotonsillectomy (AT). Risk factors for patients to have persistent disease include obesity, being Afro-Caribbean and existing co-morbidities such as craniofacial and neuromuscular disorders. Initial assessment of...CO2 Laser Dohlmans: Does It Still Have A Role In Pharyngeal Pouch Management?
Background The commonest active management of a pharyngeal pouch is the division of the “interparty” wall using a stapling device [1, 2]. The technique is relatively straight forward to perform and theoretically should have less complications than other techniques such...The costs of applying to ENT specialty training
Training doctors is costly. In the UK, medical school costs an estimated £230,000 made up of £163,000 in government grants and £65,000 in student loans [1]. Repayment of the student loan begins once the graduate earns above a certain threshold,...Audiology in this issue...IFOS Vancouver
Erica Zaia, MSc, Registered Audiologist, Certified in Vestibular Assessment and Management, Founder/Director, Audio-Vestibular Clinic, Vancouver, Canada. E: ericazaia@hotmail.com www.vestibular.ca ‘These unprecedented times.’ I believe that this is one of the most used sentences in the English language in 2020. And...ENT & Audiology in this issue...The Outer Ear
Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Priya Carling, AuD,Director and Consultant Audiologist,Kent Hearing Ltd, UK. E: priya@Kenthearing.com The outer ear is, we think, the unsung hero...
Liver function assessment in glandular fever
This month’s Editors’ Choice is a systematic review of the role of liver assessment in patients with glandular fever. Admission of patients with sore throat constitutes a significant burden of acute work for paediatric and adult ENT services as well...
