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1707 results found

GORD and CRS – is there an association?

This international collaboration assessed 32 papers which had published original data on the experimental, diagnostic, treatment or prognostic association between GORD and CRS. The study aims to systematically review the evidence for a role of GORD in CRS. Case control,...

Predicting which oropharyngeal SCC HPV-positive patients should avoid de-escalated treatment

This study is timely for many reasons and raises very important questions in the management of the current rise in HPV-positive patients with oropharyngeal cancer (OPC). The uniqueness of this group within head and neck cancer in terms of favourable...

Commercial desiccants or uncooked rice?

Moisture can damage any electronic devices including hearing aids. It is commonly known that rice can ‘rescue’ an electronic device if wetted. Authors of the below-described study researched whether uncooked rice could be used as an efficient equivalent to often...

Nasal nitric oxide – an inflammatory marker in paediatric allergic rhinitis?

Nasal nitric oxide (nNO) is mainly produced in the paranasal sinus mucosa and was shown in some studies to have increased expression in allergic rhinitis (AR). Although it represents a potential non-invasive tool for AR measurement, there remains no consensus...

Anticoagulated patients and epistaxis

This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...

SPECT-CT imaging improves surgical efficiency in sentinel lymph node biopsy in melanoma

Sentinel lymph node biopsy is used in clinically lymph node negative, primary cutaneous melanoma. A combination of planer lymposcintigraphy using a radiolabelled colloid detected intra-op by gamma probe, and cutaneous injection of blue dye is used. However, with lymphoscintigraphy spillage...

Using SNOT-22 to predict revision sinus cases

A simple way of predicting which patients will require revision endoscopic surgery does not yet exist. This study, which is a prospective, longitudinal cohort study, part of the UK national audit, aims to predict this by using a relatively simple,...

Snap: do voice patients’ self-ratings match the professionals or the machines?

Self-rating by people with voice disorders and perceptual assessments by speech and language therapists are generally quicker and cheaper than acoustic voice analysis. Reports, with small sample sizes and mixed participant groups, on whether these measures are associated have demonstrated...

Do certain chronic medications increase dysphagia in older people?

Oropharyngeal dysphagia is known to affect a high number of older people in the community, in care homes and in acute geriatric admissions to hospital. The authors of this study have recognised that many older people take drugs for chronic...

Finding the elusive parathyroid glands

While reading in the literature about new advances in knowledge and surgical techniques, it is often easy to lose track of the longstanding knowledge that we all acquired during our training. This is why this article on the anatomy and...

Incidental thyroid nodules: should we observe or operate?

Thyroid nodules are extraordinarily prevalent, detected by physical examination in 7% and by imaging studies in 67% of the population. Although most of these nodules are benign, up to 20% are found to be malignant on excision. It’s a very...

Prostaglandin versus leukotriene receptor-antagonists in treatment of seasonal allergic rhinitis RCT phase II

Seasonal allergic rhinitis is very common. Failure to control the disease with mono-therapy leads to dual therapy treatment with less compliance and reduced quality of life. A prostaglandin receptor antagonist (ONO-4053) showed some efficacy in controlling allergic rhinitis in animal...